tert-butyl N-[(3S,5S,6S,8S)-8-[(3-amino-2,2-dimethyl-3-oxopropyl)carbamoyl]-6-hydroxy-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-2,9-dimethyldecan-5-yl]carbamate

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Names

[ Name ]:
tert-butyl N-[(3S,5S,6S,8S)-8-[(3-amino-2,2-dimethyl-3-oxopropyl)carbamoyl]-6-hydroxy-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-2,9-dimethyldecan-5-yl]carbamate

Chemical & Physical Properties

[ Density]:
1.071g/cm3

[ Boiling Point ]:
810.7ºC at 760 mmHg

[ Molecular Formula ]:
C₃₅H₆₁N₃O₈

[ Molecular Weight ]:
651.87400

[ Flash Point ]:
444.1ºC

[ Exact Mass ]:
651.44600

[ PSA ]:
158.44000

[ LogP ]:
6.34160

[ Vapour Pressure ]:
8.94E-28mmHg at 25°C

[ Index of Refraction ]:
1.505

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

tert-Butyl ((1S,3S)-1-((2S,4S)-4-isopropyl-5-oxotetrahydrofuran-2-yl)-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-4-methylpentyl)carbamate
3-Amino-2,2-dimethylpropanamide
2-cyano-2-methyl-propanamide
(R)-3-(3-Methylbutanoyl)-4-benzyloxazolidin-2-one
Aliskiren inter-9
Isovanillin
4-Methoxy-3-(3-methoxypropoxy)benzaldehyde
(R)-2-[3-(3-METHOXYPROPOXY)-4-METHOXYBENZYL]-3-METHYLBUTAN-1-OL
(R)-2-[3-(3-METHOXYPROPOXY)-4-METHOXYBENZYL]-3-METHYL-BUTYRICACID

DownStream

Aliskiren
Aliskiren Hydrochloride
Aliskiren hemifumarate

Related Compounds

Ethyl 3-(ethyl 2-(2,4-dimethoxybenzylcarbamoyl)acetyl)propanoate
N-(5-bromo-1h-pyrazolo[3,4-b]pyridin-3-yl)-2-methoxyacetamide
N-(5-bromo-1h-pyrazolo[3,4-b]pyridin-3-yl)methanesulfonamide
Tert-butyl (2-(trimethylsilyl)ethoxy)methyl4-formylthiazol-2-ylcarbamate
Tert-butyl 4-(6-formylpyridin-2-yloxy)phenylcarbamate
Tert-butyl 4-(ethoxycarbonyl)-2-(3-iodophenyl)thiazol-5-ylmethylcarbamate
Tert-butyl 4-carbamoyl-2-(3-iodophenyl)thiazol-5-ylmethylcarbamate
(R)-tert-butyl 3-(2h-indazol-2-yl)pyrrolidine-1-carboxylate
3-Hydrazinyl-4-methoxy-N,N-dimethylbenzenesulfonamide
4-(Acetylamino)-N-[2-Nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzamide