Aliskiren Hydrochloride

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Names

[ CAS No. ]:
173399-03-6

[ Name ]:
Aliskiren Hydrochloride

[Synonym ]:
Aliskiren hydrochloride
AKN hydrochloride
5(S)-amino-4(S)-hydroxy-2(S),7(S)-diisopropyl-8-[4-methoxy-3-(3-methoxypropyloxy)-phenyl]-octanoic acid [N-(2-carbamoyl-2,2-dimethyl-ethyl)]-amide hydrochloride
Rasilez Hydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C30H54ClN3O6

[ Molecular Weight ]:
588.21900

[ Exact Mass ]:
587.37000

[ PSA ]:
146.13000

[ LogP ]:
5.88700

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • tert-butyl N-[(3S,5S,6S,8S)-8-[(3-amino-2,2-dimethyl-3-oxopropyl)carbamoyl]-6-hydroxy-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-2,9-dimethyldecan-5-yl]carbamate

DownStream

  • Aliskiren hemifumarate

Related Compounds

  • aliskiren hydrochloride
  • Aliskiren hydrochloride
  • Aliskiren D6 Hydrochloride
  • Aliskiren fumarate
  • carnitine hydrochloride
  • Losoxantrone hydrochloride [USAN]
  • 3-Hydroxy-1-(5-nitropyridin-2-yl)cyclobutane-1-carboxylic acid
  • {1-[(trimethyl-1H-pyrazol-4-yl)methyl]cyclopropyl}methanamine
  • 2-[1-(1,2,3-Thiadiazol-4-yl)cyclobutyl]ethan-1-amine
  • 1-(1,2,3-Thiadiazol-4-yl)cyclobutane-1-carboxylic acid
  • 2-{1-[2-(Thiophen-3-yl)ethyl]cyclopropyl}ethan-1-amine
  • methyl (3S)-3-hydroxy-3-(5-nitropyridin-2-yl)propanoate
  • (2S)-1-(5-nitropyridin-2-yl)propan-2-ol
  • 3-hydroxy-1-(1-methyl-1H-pyrazol-5-yl)cyclobutane-1-carboxylic acid
  • {1-[2-(Piperidin-1-yl)pyridin-3-yl]cyclopropyl}methanol
  • 5-[(2R)-oxiran-2-yl]-1H-1,3-benzodiazole
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