Aliskiren Hydrochloride

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Names

[ CAS No. ]:
173399-03-6

[ Name ]:
Aliskiren Hydrochloride

[Synonym ]:
Aliskiren hydrochloride
AKN hydrochloride
5(S)-amino-4(S)-hydroxy-2(S),7(S)-diisopropyl-8-[4-methoxy-3-(3-methoxypropyloxy)-phenyl]-octanoic acid [N-(2-carbamoyl-2,2-dimethyl-ethyl)]-amide hydrochloride
Rasilez Hydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C30H54ClN3O6

[ Molecular Weight ]:
588.21900

[ Exact Mass ]:
587.37000

[ PSA ]:
146.13000

[ LogP ]:
5.88700

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • tert-butyl N-[(3S,5S,6S,8S)-8-[(3-amino-2,2-dimethyl-3-oxopropyl)carbamoyl]-6-hydroxy-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-2,9-dimethyldecan-5-yl]carbamate

DownStream

  • Aliskiren hemifumarate

Related Compounds

  • aliskiren hydrochloride
  • Aliskiren hydrochloride
  • Aliskiren D6 Hydrochloride
  • Aliskiren fumarate
  • carnitine hydrochloride
  • Losoxantrone hydrochloride [USAN]
  • (2E)-2-[(5-methoxy-1-methyl-1H-indol-3-yl)methylidene]-7-methyl-3-oxo-2,3-dihydro-1-benzofuran-6-yl 2-methoxybenzoate
  • Tert-butyl 2-ethynyl-5-oxopyrrolidine-1-carboxylate
  • Methyl 4-({6-[(4-methylphenyl)sulfonyloxy]-3-oxobenzo[d]furan-2-ylidene}methyl)benzoate
  • 4-Amino-5,5-dimethylpyrrolidin-2-one
  • 2-(3,4-dimethoxyphenyl)-N-[(2Z)-3-methyl-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]acetamide
  • 5-(Hydroxymethyl)-5-methyl-1,3-oxazinan-2-one
  • 5,6-dimethyl-N-[3-(morpholin-4-yl)propyl]-7-(pyridin-4-ylmethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
  • 2-(benzo[d][1,3]dioxol-5-yl)-N-((3-(1-methyl-1H-pyrazol-4-yl)pyrazin-2-yl)methyl)acetamide
  • 2-{(1E)-5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl}-N-(3-hydroxyphenyl)acetamide
  • N-((3-(1-methyl-1H-pyrazol-4-yl)pyrazin-2-yl)methyl)benzo[b]thiophene-2-carboxamide