1-[2-chloroethyl(methylsulfonyl)amino]-3-methyl-1-methylsulfonylurea

Names

[ CAS No. ]:
173424-77-6

[ Name ]:
1-[2-chloroethyl(methylsulfonyl)amino]-3-methyl-1-methylsulfonylurea

[Synonym ]:
Cloretazine
1,2-bis(methylsulfonyl)-1-(2-chlorchloroethyl)-2--2-(methylaminocarbonyl)hydrazine
Onrigin
Laromustine (USAN)
Laromustine
101M
1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]-hydrazine

Chemical & Physical Properties

[ Density]:
1.527g/cm3

[ Molecular Formula ]:
C6H14ClN3O5S2

[ Molecular Weight ]:
307.77500

[ Exact Mass ]:
307.00600

[ PSA ]:
120.62000

[ LogP ]:
1.55530

[ Index of Refraction ]:
1.546

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • phosgene
  • 1,2-BIS(METHYLSULFONYL)-1-(2-CHLOROETHYL)HYDRAZINE
  • methylamine
  • 1,2-BIS(METHYLSULFONYL)-1-{2-[(METHYLSULFONYL)OXY]ETHYL}HYDRAZINE
  • Methylcarbamic chloride
  • Methylisocyanate 1 x 500mg neat

DownStream

  • 2-Chloroethanol
  • 1-benzyl-3-methyl-urea

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • Bis(2-pyridylmethyl)octadecylamine
  • 1-[(Ethylcarbamoyl)amino]-1-oxopropan-2-yl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • (1S)-1-[4-(methylsulfanyl)phenyl]ethan-1-ol