a-methyl-D-phenylalanine

Suppliers

Names

[ Name ]:
a-methyl-D-phenylalanine

[Synonym ]:
(R )-2-Amino-2-methyl-3-phenylpropionic acid
(R)-2-amimo-2-methyl-3-phenylpropanoic acid
(S)-2-Amino-2- Methyl-3-Phenylpropanoic Acid
D-Phenylalanine, α-methyl-
2-Methyl-D-phenylalanine
(R)-alpha-Methylphenylalanine hydrate
a-methyl-D-phenylalanine
MFCD00153491
D-phenylalanine, a-methyl-
α-Methyl-D-phenylalanine
(R)-2-Amino-2-methyl-3-phenylpropanoic acid
D-α-methylphenylalanine

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
312.8±30.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₃NO₂

[ Molecular Weight ]:
179.216

[ Flash Point ]:
143.0±24.6 °C

[ Exact Mass ]:
179.094635

[ PSA ]:
63.32000

[ LogP ]:
1.46

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.566

[ Storage condition ]:
Store at RT.

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(R)-2-ACETAMIDO-3-(4-CHLOROPHENYL)PROPANOICACID
tert-butyl 2-methyl-2-((S)-2-phenoxy-3-phenylpropanamido)-3-phenylpropanoate
Benzyl bromide
(R)-tert-butyl 2-methyl-2-((3S,4R)-2-oxo-3-phenoxy-4-phenylazetidin-1-yl)-3-phenylpropanoate
(R)-3-benzyl-7-chloro-1-isopropyl-3-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Effects of dietary mixtures of amino acids on fetal growth and maternal and fetal amino acid pools in experimental maternal phenylketonuria.

Am. J. Clin. Nutr. 69(4) , 687-96, (1999)

Branched-chain amino acids have been reported to improve fetal brain development in a rat model in which maternal phenylketonuria (PKU) is induced by the inclusion of an inhibitor of phenylalanine hyd...

Inhibition of brain and liver 3-hydroxy-3-methylglutaryl-CoA reductase and mevalonate-5-pyrophosphate decarboxylase in experimental hyperphenylalaninemia.

Neurochem. Res. 13(6) , 551-5, (1988)

Experimental hyperphenylalaninemia has been induced in 5-day-old chicks by dietary treatments with phenylalanine and alpha-methylphenylalanine. An increase of nearly 8-fold in plasma Phe/Tyr ratio was...

Effect of phenylalanine and its metabolites on ATP diphosphohydrolase activity in synaptosomes from rat cerebral cortex.

Neurochem. Res. 19(9) , 1175-80, (1994)

The in vitro effects of phenylalanine and some of its metabolites on ATP diphosphohydrolase (apyrase, EC 3.6.1.5) activity in synaptosomes from rat cerebral cortex were investigated. The enzyme activi...

N-[(1,1-Dimethylethoxy)Carbonyl]-alpha-Methyl-D-Phenylalanine
N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-alpha-Methyl-D-Phenylalanine
a-methyl-D-tyrosine
4-Methyl-D-phenylalanine
N-methyl-D-phenylalanine ethyl ester; hydrochloride
Bilaid A
7,8-Dichlorothiochroman-4-amine
3-iodo-2-methyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-5,7-dione
3-(6-Bromopyridin-3-yl)cyclopentan-1-one
Methyl 3,4-dihydro-1H-2-benzopyran-7-carboxylate
4-(Trifluoromethyl)-2,3-dihydro-1-benzofuran
Methyl 2,3-dihydrobenzofuran-4-carboxylate
Methyl 2-amino-3-hydroxy-2-(hydroxymethyl)propanoate
5-Nitro-1,2,3,4-tetrahydroquinolin-4-amine
12,12,13,13,14,14,15,15,16,16,17,17,17-Tridecafluoroheptadecyltriethoxysilane
12,12,13,13,14,14,15,15,15-Nonafluoropentadecyltriethoxysilane

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