dehydroabietic acid
Suppliers
Names
[ CAS No. ]:
1740-19-8
[ Name ]:
dehydroabietic acid
[Synonym ]:
dehydroabietic acid
abietic acid, dehydro-
1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylic acid
(+)-Dehydroabietic acid
1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aS,10aR)-
Abieta-8(14),9(11),12-trien-18-oic acid
Abieta-8,11,13-trien-18-oic acid,Dehydroabietate
EINECS 217-102-8
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
425.1±34.0 °C at 760 mmHg
[ Melting Point ]:
174-176ºC
[ Molecular Formula ]:
C20H28O2
[ Molecular Weight ]:
300.435
[ Flash Point ]:
202.5±20.3 °C
[ Exact Mass ]:
300.208923
[ PSA ]:
37.30000
[ LogP ]:
6.35
[ Appearance of Characters ]:
NA
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.540
[ Storage condition ]:
?20°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TP8710000
- CHEMICAL NAME :
- Podocarpa-8,11,13-trien-15-oic acid, 13-isopropyl-
- CAS REGISTRY NUMBER :
- 1740-19-8
- BEILSTEIN REFERENCE NO. :
- 2059290
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C20-H28-O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1710 mg/kg
- TOXIC EFFECTS :
- Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - ataxia
- REFERENCE :
- BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 18,42,1977 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8400 mg/kg/28D-C
- TOXIC EFFECTS :
- Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Metabolism (Intermediary) - Plasma proteins not involving coagulation
- REFERENCE :
- BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 18,42,1977 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2653 No. of Facilities: 1630 (estimated) No. of Industries: 16 No. of Occupations: 20 No. of Employees: 13811 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2653 No. of Facilities: 394 (estimated) No. of Industries: 8 No. of Occupations: 12 No. of Employees: 14625 (estimated) No. of Female Employees: 4688 (estimated)
Safety Information
[ Symbol ]:
GHS06, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H410
[ Precautionary Statements ]:
P273-P301 + P310-P501
[ Hazard Codes ]:
T,N
[ Risk Phrases ]:
25-50
[ Safety Phrases ]:
45-61
[ RIDADR ]:
UN 2811 6.1 / PGIII
Precursor & DownStream
Precursor
DownStream
Articles
J. Chromatogr. A. 1371 , 20-9, (2014)
Two resin acids, abietic acid (AA) and dehydroabietic acid (DHAA), in cosmetics may cause allergy or toxicoderma, but remain inaccurately investigated due to their lability. In this work, an accurate,...
Dermatitis 21(3) , 157-9, (2010)
Allergic contact dermatitis (ACD) is a well-recognized immune-mediated disease often associated with the use of vulcanization accelerator-containing latex and nitrile gloves. Potential contact allerge...
Molecules 17(4) , 4634-50, (2012)
A series of new N-acylhydrazone derivatives were synthesized in good yields through the reactions of dehydroabietic acid hydrazide with a variety of substituted arylaldehydes. The structures of the sy...