Tipranavir

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Names

[ CAS No. ]:
174484-41-4

[ Name ]:
Tipranavir

[Synonym ]:
Aptivus
2o4l
Tipranavir
1d4y
UNII-ZZT404XD09
N-[3-[(1R)-1-[(2R)-4-hydroxy-6-oxo-2-(2-phenylethyl)-2-propyl-3H-pyran-5-yl]propyl]phenyl]-5-(trifluoromethyl)pyridine-2-sulfonamide

Chemical & Physical Properties

[ Density]:
1.313g/cm3

[ Boiling Point ]:
680ºC at 760mmHg

[ Melting Point ]:
86-89ºC

[ Molecular Formula ]:
C31H33F3N2O5S

[ Molecular Weight ]:
602.66400

[ Flash Point ]:
365.1ºC

[ Exact Mass ]:
602.20600

[ PSA ]:
113.97000

[ LogP ]:
8.47930

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.579

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-(Trifluoromethyl)-2-pyridinesulfonyl chloride
  • (R)-3-((R)-1-(3-aminophenyl)propyl)-4-hydroxy-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-2-one
  • (E)-1-Chloro-2-pentene-1-one
  • (4R)-3-[(3S)-3-[3-(dibenzylamino)phenyl]pentanoyl]-4-phenyl-1,3-oxazolidin-2-one
  • [R-(R*,R*)]-3-[1-[3-[Bis(phenylmethyl)amino]phenyl]propyl]-5,6-dihydro-4-hydroxy-6-(2-phenylethyl)-6-(1-propynyl)-2H-pyran-2-one
  • (4R)-3-[(2S,3S)-2-Acetyl-3-[3-[bis(phenylmethyl)amino]phenyl]-1-oxopentyl]-4-phenyl-2-oxazolidinone
  • (2S,5R)-2-[(1S)-1-[3-(dibenzylamino)phenyl]propyl]-5-hydroxy-1-[(4R)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-5-(2-phenylethyl)oct-6-yne-1,3-dione
  • [R-(E)]-3-(1-Oxo-2-pentenyl)-4-phenyl-2-oxazolidinone
  • 1-phenylhexan-3-one
  • 3-Nitrobenzaldehyde

DownStream

Related Compounds

  • TIPRANAVIR
  • tipranavir
  • Tipranavir
  • N-Hydroxy Tipranavir
  • Tipranavir Glucuronide
  • N-Hydroxy Tipranavir-d5
  • Tert-butyl 4-(3-amino-4-hydroxybutyl)piperazine-1-carboxylate
  • {2-[(2-Iodocyclopentyl)oxy]ethoxy}cyclohexane
  • tert-butyl N-(3-amino-2-methyl-2-{pyrazolo[1,5-a]pyridin-3-yl}propyl)carbamate
  • 2-(2,5-Dimethylthiophen-3-yl)-2-methylpropanenitrile
  • 4-[Amino(thiophen-3-yl)methyl]-2,2,6,6-tetramethylpiperidin-4-ol
  • 4-(2-Ethynylphenyl)butan-2-amine
  • (2R)-4-(1H-indol-6-yl)butan-2-ol
  • 3-(2-{[(Tert-butoxy)carbonyl]amino}pyrimidin-5-yl)-2-hydroxypropanoic acid
  • 4-[(Pyrazin-2-yl)methyl]piperidin-4-ol
  • (1-(4-Bromophenyl)-1H-pyrazol-3-yl)methanamine dihydrochloride
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