Tipranavir

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Names

[ CAS No. ]:
174484-41-4

[ Name ]:
Tipranavir

[Synonym ]:
Aptivus
2o4l
Tipranavir
1d4y
UNII-ZZT404XD09
N-[3-[(1R)-1-[(2R)-4-hydroxy-6-oxo-2-(2-phenylethyl)-2-propyl-3H-pyran-5-yl]propyl]phenyl]-5-(trifluoromethyl)pyridine-2-sulfonamide

Chemical & Physical Properties

[ Density]:
1.313g/cm3

[ Boiling Point ]:
680ºC at 760mmHg

[ Melting Point ]:
86-89ºC

[ Molecular Formula ]:
C31H33F3N2O5S

[ Molecular Weight ]:
602.66400

[ Flash Point ]:
365.1ºC

[ Exact Mass ]:
602.20600

[ PSA ]:
113.97000

[ LogP ]:
8.47930

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.579

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-(Trifluoromethyl)-2-pyridinesulfonyl chloride
  • (R)-3-((R)-1-(3-aminophenyl)propyl)-4-hydroxy-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-2-one
  • (E)-1-Chloro-2-pentene-1-one
  • (4R)-3-[(3S)-3-[3-(dibenzylamino)phenyl]pentanoyl]-4-phenyl-1,3-oxazolidin-2-one
  • [R-(R*,R*)]-3-[1-[3-[Bis(phenylmethyl)amino]phenyl]propyl]-5,6-dihydro-4-hydroxy-6-(2-phenylethyl)-6-(1-propynyl)-2H-pyran-2-one
  • (4R)-3-[(2S,3S)-2-Acetyl-3-[3-[bis(phenylmethyl)amino]phenyl]-1-oxopentyl]-4-phenyl-2-oxazolidinone
  • (2S,5R)-2-[(1S)-1-[3-(dibenzylamino)phenyl]propyl]-5-hydroxy-1-[(4R)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-5-(2-phenylethyl)oct-6-yne-1,3-dione
  • [R-(E)]-3-(1-Oxo-2-pentenyl)-4-phenyl-2-oxazolidinone
  • 1-phenylhexan-3-one
  • 3-Nitrobenzaldehyde

DownStream

Related Compounds

  • TIPRANAVIR
  • tipranavir
  • Tipranavir
  • N-Hydroxy Tipranavir
  • Tipranavir Glucuronide
  • N-Hydroxy Tipranavir-d5
  • 2,3,4,6-Tetrabromo-5-methoxy-N-methylaniline
  • 5-Chloro-2-cyclopropyl-6-(cyclopropyl(methyl)amino)pyrimidine-4-carboxylic acid
  • 5-Hydroxy-3,4-bis(hydroxymethyl)-6-methylpicolinaldehyde
  • Methyl 6-cyano-2-formylnicotinate
  • 5-Benzyl-[3,3'-bipyridine]-2,2'-dicarboxylic acid
  • 5-Chloro-2-cyclopropyl-6-(methyl(2-phenylcyclopropyl)amino)pyrimidine-4-carboxylic acid
  • 7-(1-(((Tert-butoxycarbonyl)amino)methyl)cyclohexyl)-2-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid
  • 6-Ethoxy-5-methylpicolinaldehyde
  • [2,4'-Bipyridine]-3',5-dicarboxylic acid
  • 5-Methyl-[3,3'-bipyridine]-2,2'-dicarboxylic acid
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