monolinuron
Suppliers
Names
[ CAS No. ]:
1746-81-2
[ Name ]:
monolinuron
[Synonym ]:
N’-(4-chlorophenyl)-N-methoxy-N-methylurea
3-(4-Chlorophenyl)-1-methoxy-1-methylurea
Monolinuron
MFCD00055264
EINECS 217-129-5
Urea, N'-(4-chlorophenyl)-N-methoxy-N-methyl-
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Melting Point ]:
76-78ºC
[ Molecular Formula ]:
C9H11ClN2O2
[ Molecular Weight ]:
214.649
[ Flash Point ]:
100 °C
[ Exact Mass ]:
214.050903
[ PSA ]:
41.57000
[ LogP ]:
2.30
[ Index of Refraction ]:
1.590
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YS6425000
- CHEMICAL NAME :
- Urea, 3-(p-chlorophenyl)-1-methoxy-1-methyl-
- CAS REGISTRY NUMBER :
- 1746-81-2
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C9-H11-Cl-N2-O2
- MOLECULAR WEIGHT :
- 214.67
- WISWESSER LINE NOTATION :
- GR DMVN1&O1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued. Volume(issue)/page/year: 9,119,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969 Volume(issue)/page/year: 5,158,1976 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 8 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death
- REFERENCE :
- ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 38,261,1977
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 8 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- REFERENCE :
- ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 38,261,1977
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 4 gm/kg
- SEX/DURATION :
- female 10-13 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 38,261,1977
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)
- REFERENCE :
- ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 38,261,1977 *** REVIEWS *** TOXICOLOGY REVIEW DTTIAF Deutsche Tieraerztliche Wochenschrift. (Hanover, Fed. Rep. Ger.) V.1-77, 1893-1970. Volume(issue)/page/year: 80,485,1973
Safety Information
[ Symbol ]:
GHS07, GHS08, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H373-H410
[ Precautionary Statements ]:
P273-P501
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;N: Dangerous for the environment;
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
22-60-61
[ RIDADR ]:
UN 3077 9/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
YS6425000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Chromatogr. A. 1364 , 96-106, (2014)
Highly cross-linked monolithic networks (i.e., polyethylene glycol diacrylate, PEGDA) synthesized from monomers containing varying ethylene oxide chain lengths were fabricated inside fused silica capi...
Ultrason. Sonochem. 18(5) , 1107-12, (2011)
Highlights ► Monolinuron is degraded by ultrasounds by OH or CO 3 - radicals. ► Ultrasound efficiency was improved in the presence of nanoparticles of TiO 2 and SiO 2 only at 20 kHz. ► Activated speci...
Environ. Sci. Pollut. Res. Int. 18(6) , 949-57, (2011)
Photodegradation and hydrolysis of two substituted urea herbicides, monolinuron [3-(4-chlorophenyl)-1-methoxy-1-methylurea] and linuron [3-(3,4-dichlorophenyl)-1-methoxy-1-methylurea], and one organop...