SB-222200
Suppliers
Names
Chemical & Physical Properties
[ Density]:
1.142g/cm3
[ Boiling Point ]:
553.5ºC at 760 mmHg
[ Molecular Formula ]:
C26H24N2O
[ Molecular Weight ]:
380.48200
[ Flash Point ]:
288.6ºC
[ Exact Mass ]:
380.18900
[ PSA ]:
41.99000
[ LogP ]:
6.48220
[ Vapour Pressure ]:
2.7E-12mmHg at 25°C
[ Index of Refraction ]:
1.633
[ Storage condition ]:
2-8℃
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
Articles
J. Pharmacol. Exp. Ther. 295(1) , 373-81, (2000)
The pharmacological and pharmacokinetic profile of SB-222200 [(S)-(-)-N-(alpha-ethylbenzyl)-3-methyl-2-phenylquinoline-4-car boxami de], a human NK-3 receptor (hNK-3R) antagonist, was determined. SB-2...
Br. J. Pharmacol. 122 , 469-476, (1997)
1. Inhibition of NK3 receptor agonist-induced contraction in the rabbit isolated iris sphincter muscle was used to assess the in vitro functional activity of three 2-phenyl-4-quinolinecarboxamides, me...
Hum. Reprod. 29(12) , 2736-46, (2014)
Are neurokinin B (NKB), NK3 receptor (NK3R), kisspeptin (KISS1) and kisspeptin receptor (KISS1R) expressed in human ovarian granulosa cells?The NKB/NK3R and kisspeptin/KISS1R systems are co-expressed ...