(R)-(3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

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Names

[ CAS No. ]:
174649-09-3

[ Name ]:
(R)-(3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

[Synonym ]:
[(5R)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl methanesulfonate
{(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl methanesulfonate
(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-5-[[(methylsulfonyl)oxy]methyl]-2-oxazolidinone
(R)-[3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methyl methanesulfonate
2-Oxazolidinone, 3-[3-fluoro-4-(4-morpholinyl)phenyl]-5-[[(methylsulfonyl)oxy]methyl]-, (5R)-
Linezolid Impurity 32

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
592.7±50.0 °C at 760 mmHg

[ Melting Point ]:
183-185ºC

[ Molecular Formula ]:
C15H19FN2O6S

[ Molecular Weight ]:
374.385

[ Flash Point ]:
312.3±30.1 °C

[ Exact Mass ]:
374.094788

[ PSA ]:
93.76000

[ LogP ]:
0.79

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.568

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methanesulfonyl chloride
  • (R)-3-(3-Fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one
  • 3,4-Difluoronitrobenzene
  • 4-(2-Fluoro-4-nitrophenyl)morpholine
  • 3-Fluoro-4-morpholinoaniline
  • (3-Fluoro-4-morpholin-4-ylphenyl)carbamic acid benzyl ester

DownStream

  • Deacetyl Linezolid
  • Linezolid
  • (R)-5-(Azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone
  • (R)-N-[[3-[3-Fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]phthalimide

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%