3-Cyclohexene-1-carboxylicacid, 3-ethyl-4-(4-methoxyphenyl)-2-methyl-
Suppliers
Names
[ CAS No. ]:
1755-52-8
[ Name ]:
3-Cyclohexene-1-carboxylicacid, 3-ethyl-4-(4-methoxyphenyl)-2-methyl-
[Synonym ]:
3-Cyclohexene-1-carboxylic acid,3-ethyl-4-(p-methoxyphenyl)-2-methyl
ORF 2166
3-Aethyl-4-(4-methoxy-phenyl)-2-methyl-cyclohex-3-encarbonsaeure
3-Ethyl-4-(p-methoxyphenyl)-2-methyl-3-cyclohexene-1-carboxylic acid
U 2911
3-ethyl-4-(4-methoxy-phenyl)-2-methyl-cyclohex-3-enecarboxylic acid
CARBESTROL
Chemical & Physical Properties
[ Density]:
1.081g/cm3
[ Boiling Point ]:
426.1ºC at 760mmHg
[ Molecular Formula ]:
C17H22O3
[ Molecular Weight ]:
274.35500
[ Flash Point ]:
152.3ºC
[ Exact Mass ]:
274.15700
[ PSA ]:
46.53000
[ LogP ]:
3.98950
[ Vapour Pressure ]:
5.09E-08mmHg at 25°C
[ Index of Refraction ]:
1.531
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GW4430000
- CHEMICAL NAME :
- 3-Cyclohexene-1-carboxylic acid, 3-ethyl-4-(p-methoxyphenyl)-2-methyl-
- CAS REGISTRY NUMBER :
- 1755-52-8
- BEILSTEIN REFERENCE NO. :
- 2653888
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C17-H22-O3
- MOLECULAR WEIGHT :
- 274.39
- WISWESSER LINE NOTATION :
- L6UTJ AR DO1& B2 C1 DVQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 126 mg/kg/6W-I
- TOXIC EFFECTS :
- Behavioral - anorexia (human) Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting
- REFERENCE :
- CCROBU Cancer Chemotherapy Reports, Part 1. (Washington, DC) V.52(6)-59, 1968-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 56,641,1972 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 16 mg/kg
- SEX/DURATION :
- male 8 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 12,381,1966
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 30 ug/kg
- SEX/DURATION :
- female 1 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 167,105,1969
Safety Information
[ HS Code ]:
2918990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2918990090
[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%