2-Hydroxy-5-iodobenzaldehyde

Names

[ CAS No. ]:
1761-62-2

[ Name ]:
2-Hydroxy-5-iodobenzaldehyde

[Synonym ]:
2-HYDROXY-5-IODOBENZALDEHYDE
5-Iodosalicylaldehyde
MFCD00723501

Chemical & Physical Properties

[ Density]:
30 g/mL at 25 °C(lit.)

[ Boiling Point ]:
282ºC at 760 mmHg

[ Melting Point ]:
98-100 °C(lit.)

[ Molecular Formula ]:
C₇H₅IO₂

[ Molecular Weight ]:
248.01800

[ Flash Point ]:
124.3ºC

[ Exact Mass ]:
247.93300

[ PSA ]:
37.30000

[ LogP ]:
1.80930

[ Vapour Pressure ]:
0.00202mmHg at 25°C

[ Index of Refraction ]:
1.715

[ Storage condition ]:
Store Cold

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2913000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Salicylaldehyde
Formaldehyde
4-Iodophenol
Salicylic acid
6-iodo-2,2-dimethylbenzo[1,3]dioxin-4-one
2-HYDROXY-5-IODOBENZYL ALCOHOL
2-Methylbenzyl Alcohol
5-Iodosalicylic acid
molecular iodine

DownStream

5-Iodo-2-methoxybenzaldehyde
5-Formylsalicylaldehyde
2-HYDROXY-5-IODOBENZYL ALCOHOL
(5-FLUORO-2-METHOXY-PYRIDIN-3-YL)-METHYLAMINE
ethyl 5-iodo-1-benzofuran-2-carboxylate

Customs

[ HS Code ]: 2913000090

[ Summary ]:
HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

Articles

An efficient and convenient synthesis of 5-formylsalicylaldehyde. Lee SH, et al.

Synth. Commun. 30(6) , 1003-1008, (2000)

Synthesis of 5-ortho-Carboranylsalicylaldehyde and an Indolinospirobenzopyran. Lee SH, et al.

Synth. Commun. 39(22) , 4069-4078, (2009)

Synthesis and catalytic properties of p-acylthio (phenylacetylene) n substituted chiral manganese salen complexes. Nielsen M and Gothelf KV.

J. Chem. Soc. Perkin Trans. I 19 , (2001)

3-tert-butyl-2-hydroxy-5-iodobenzaldehyde
2-Hydroxy-5-methyl-3-(1-piperidinyl)-2-cyclopenten-1-one
2-hydroxy-5-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]benzamide
[2-hydroxy-5-[hydroxy(piperidin-2-yl)methyl]phenyl]urea,hydrochloride
2-hydroxy-5-(4-methylphenyl)sulfonylbenzonitrile
2-hydroxy-5-(4-methylphenyl)sulfonylbenzamide
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
[2,2-Difluoro-1-(4-nitrophenyl)cyclopropyl]methanamine
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide