5-Chlorooxindole

Suppliers

Names

[ CAS No. ]:
17630-75-0

[ Name ]:
5-Chlorooxindole

[Synonym ]:
5-Chlorooxindole
EINECS 412-200-9
2H-Indol-2-one, 5-chloro-1,3-dihydro-
5-chloroindolin-2-one
5-Chloro-1,3-dihydro-2H-indol-2-one
5-Chloro-2-oxindole
5-chloro-1,3-dihydroindol-2-one
5-Chloro-2-indolinone
MFCD00191927

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
348.3±42.0 °C at 760 mmHg

[ Melting Point ]:
194-197 °C(lit.)

[ Molecular Formula ]:
C8H6ClNO

[ Molecular Weight ]:
167.592

[ Flash Point ]:
164.5±27.9 °C

[ Exact Mass ]:
167.013794

[ PSA ]:
29.10000

[ LogP ]:
2.12

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.602

[ Storage condition ]:
Keep Cold

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H317-H361f-H412

[ Precautionary Statements ]:
P273-P280

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38;R43;R62

[ Safety Phrases ]:
S22-S36/37-S61-S45-S36/37/39-S24

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ HS Code ]:
2933790090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-Chloroindoline-2,3-dione
  • (5-chloro-2-nitro-phenyl)acetic acid methyl ester
  • 2-(5-chloro-2-nitrophenyl)acetic acid
  • 5-chloro-3-diazo-1,3-dihydro-2H-indol-2-one
  • (2-Bromo-5-chlorophenyl)acetonitrile
  • 1,3-dihydro-1-Methoxy-2H-Indol-2-one
  • 4-Chloroaniline
  • Chloroacetyl chloride

DownStream

  • N-benzoyl-5-chloro-2-oxo-3H-indole-1-carboxamide
  • CP-66248
  • 5-Chloroindoline-2,3-dione
  • 3,3-DIBROMO-5-CHLORO-1,3-DIHYDROINDOL-2-ONE
  • 5-CHLORO-1,3-DIHYDRO-INDOLE-2-THIONE
  • 2H-Indol-2-one,5-chloro-1,3-dihydro-3-(1-methyl-2-pyrrolidinylidene)-

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Articles

Assay and purity evaluation of 5-chlorooxindole by liquid chromatography.

J. Pharm. Biomed. Anal. 14(7) , 825-33, (1996)

5-Chlorooxindole (5-CO) is a starting material for tenidap sodium, a pharmaceutical drug candidate produced by Pfizer. To insure potency and purity of the drug substance, it is necessary to demonstrat...

Synthesis and biological evaluation of new pyridone-annelated isoindigos as anti-proliferative agents.

Molecules 19(9) , 13076-92, (2014)

A selected set of substituted pyridone-annelated isoindigos 3a-f has been synthesized via interaction of 5- and 6-substituted oxindoles 2a-f with 6-ethyl-1,2,9-trioxopyrrolo[3,2-f]quinoline-8-carboxyl...


More Articles

Related Compounds

  • 5-Chlorooxindole
  • 5-Chlorooxindole
  • 3-Methyl-5-chlorooxindole
  • (E)-3-benzylidene-5-chlorooxindole
  • 1-(N-benzoylcarbamoyl)-5-chlorooxindole
  • N,O-di(phenoxycarbonyl)-5-chlorooxindole
  • (3S)-3-[6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4-dimethylhexanamido]butanoic acid
  • 1-{7-sulfanyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl}propan-2-ol
  • 2-Bromo-2-methylpropyl 2-methylpentanoate
  • 4-bromo-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methoxypropanamido]benzoic acid
  • (2S)-3-(dimethylamino)-2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1,3-thiazol-4-yl]acetamido}propanoic acid
  • 2-(3-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hex-5-enamido]methyl}cyclobutyl)acetic acid
  • (2R)-2-amino-3-(thiolan-2-yl)propanoic acid
  • (2S)-2-amino-4-(2,2-difluorocyclopropoxy)butanoic acid
  • (2R)-2-amino-4-(oxolan-3-yloxy)butanoic acid
  • 2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-{spiro[2.2]pentan-1-yl}propanoic acid
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