N-Boc-trans-4-N-Fmoc-amino-L-proline

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Names

[ CAS No. ]:
176486-63-8

[ Name ]:
N-Boc-trans-4-N-Fmoc-amino-L-proline

[Synonym ]:
(4R)-1-(tert-butoxycarbonyl)-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-L-proline
N-BOC-TRANS-4-N-FMOC-AMINO-L-PROLINE
RARECHEM EM WB 0068
(4R)-4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-proline
1,2-Pyrrolidinedicarboxylic acid, 4-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, 1-(1,1-dimethylethyl) ester, (2S,4R)-
MFCD00673783

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
650.2±55.0 °C at 760 mmHg

[ Melting Point ]:
199ºC(lit.)

[ Molecular Formula ]:
C25H28N2O6

[ Molecular Weight ]:
452.500

[ Flash Point ]:
347.0±31.5 °C

[ Exact Mass ]:
452.194733

[ PSA ]:
105.17000

[ LogP ]:
3.86

[ Appearance of Characters ]:
Powder | White/off-white/palebrown

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.627

[ Storage condition ]:
Store at 0-5°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
22

[ Safety Phrases ]:
36/37/38

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Fmoc-Osu
  • (2S,4R)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxy

DownStream

  • GAP-134
  • (2S,4R)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxy

Related Compounds

  • N-Boc-trans-4-amino-L-proline methyl ester
  • N-Boc-cis-4-Fmoc-Amino-L-proline
  • N-Boc-trans-4-amino-L-proline methyl ester hydrochloride
  • n-boc-trans-4-cyano-l-proline
  • N-BOC-TRANS-4-IODO-L-PROLINE METHYL ESTER
  • (2S,4R)-4-[tert-butyl(dimethyl)silyl]oxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid