penflutizide

Suppliers

Names

[ Name ]:
penflutizide

[Synonym ]:
FT 124
penflutizide
Penfluzide
Pentylhydroflumethiazide
3-Pentyl-7-sulfamoyl-6-trifluormethyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxid

Chemical & Physical Properties

[ Density]:
1.411g/cm3

[ Boiling Point ]:
547.4ºC at 760 mmHg

[ Molecular Formula ]:
C₁₃H₁₈F₃N₃O₄S₂

[ Molecular Weight ]:
401.42500

[ Flash Point ]:
284.8ºC

[ Exact Mass ]:
401.06900

[ PSA ]:
135.12000

[ LogP ]:
5.29170

[ Vapour Pressure ]:
4.92E-12mmHg at 25°C

[ Index of Refraction ]:
1.516

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DK9624200

CHEMICAL NAME :: 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-3-pentyl-6-(trifluoromethyl)-, 1,1-dioxide

CAS REGISTRY NUMBER :: 1766-91-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C13-H18-F3-N3-O4-S2

MOLECULAR WEIGHT :: 401.46

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >50 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >20 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >20 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >7500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979

Safety Information

[ HS Code ]:
2935009090

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Related Compounds

penflutizide
penflutizide
5-(3,3-Difluorocyclobutyl)-1,3-oxazol-2-amine
7-methyl-2-(oxan-4-yl)-2H,5H,6H,7H-pyrazolo[3,4-e][1,3]oxazin-5-one
2-{2-[(1-Benzothiophen-7-yl)amino]ethoxy}ethan-1-ol
N-(3-ethoxypropyl)-1-methyl-2,3-dihydro-1H-indol-5-amine
1-methyl-N-(3-methylbut-2-en-1-yl)-2,3-dihydro-1H-indol-5-amine
tert-butyl N-[6-(aminomethyl)pyridin-3-yl]-N-(pentan-3-yl)carbamate
tert-butyl N-({5-[ethyl(methyl)amino]piperidin-2-yl}methyl)carbamate
1-(3,4-Dipropoxyphenyl)-2-fluoroethan-1-amine
3-(But-3-en-2-yl)-1-(1-hydroxybutan-2-yl)thiourea
1-(But-3-en-2-yl)-3-(2,2,2-trifluoroethyl)thiourea

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