2,3-Dimethyl-3H-quinazolin-4-one

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Names

[ CAS No. ]:
1769-25-1

[ Name ]:
2,3-Dimethyl-3H-quinazolin-4-one

[Synonym ]:
2,3-dimethylquinazolin-4(3H)-one
2,3-Dimethyl-3H-chinazolin-4-on
B 265
2,3-dimethyl-3H-quinazolin-4-one
2,3-dimethyl-4(3H)-quinazolinone
4(3H)-Quinazolinone,2,3-dimethyl
2.3-Dimethyl-chinazolon-(4)
2,3-Dimethyl-chinazolinone(4) [German]
Dimethylquinazolone

Chemical & Physical Properties

[ Density]:
1.18g/cm3

[ Boiling Point ]:
303ºC at 760 mmHg

[ Molecular Formula ]:
C10H10N2O

[ Molecular Weight ]:
174.19900

[ Flash Point ]:
137ºC

[ Exact Mass ]:
174.07900

[ PSA ]:
34.89000

[ LogP ]:
1.24190

[ Vapour Pressure ]:
0.000957mmHg at 25°C

[ Index of Refraction ]:
1.608

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA3314500
CHEMICAL NAME :
4(3H)-Quinazolinone, 2,3-dimethyl-
CAS REGISTRY NUMBER :
1769-25-1
BEILSTEIN REFERENCE NO. :
0131970
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H10-N2-O
MOLECULAR WEIGHT :
174.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 13,688,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
85 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Behavioral - stiffness
REFERENCE :
IJMRAQ Indian Journal of Medical Research. (Indian Council of Medical Research, Ansari Nagar, New Delhi 110 029, India) V.1- 1913- Volume(issue)/page/year: 69,1008,1979

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-acetyl-N-methyl-2-nitrobenzamide
  • 2-Methylquinazolin-4-ol
  • Dimethyl sulfate
  • methyl iodide
  • N-acetyl-anthranilic acid methylamide
  • 2-iodo-N-methylbenzamide
  • acetamidine

DownStream

  • 4-Chloro-2-(trichloromethyl)quinazoline

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 6-chloro-2,3-dimethyl-3H-quinazolin-4-one
  • 8-methoxy-2,3-dimethyl-3H-quinazolin-4-one
  • 8-hydroxy-2,3-dimethyl-3H-quinazolin-4-one
  • 6,7-dimethoxy-2,3-dimethyl-3H-quinazolin-4-one
  • 2,3-diethylquinazolin-4-one
  • 2-(3-hydroxypropylamino)-4-quinazolinone