3,4,5-trifluorobenzoyl chloride

Names

[ CAS No. ]:
177787-26-7

[ Name ]:
3,4,5-trifluorobenzoyl chloride

[Synonym ]:
3,4,5-trifluorobenzoylchloride
3,4,5-Trifluorobenzoyl chloride
MFCD00083526

Chemical & Physical Properties

[ Density]:
1.4850 g/mL at 25 °C(lit.)

[ Boiling Point ]:
173-174 °C(lit.)

[ Melting Point ]:
122-123℃

[ Molecular Formula ]:
C₇H₂ClF₃O

[ Molecular Weight ]:
194.53800

[ Flash Point ]:
154 °F

[ Exact Mass ]:
193.97500

[ PSA ]:
17.07000

[ LogP ]:
2.48290

[ Vapour Pressure ]:
0.722mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.4900(lit.)

MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S27-S36/37/39-S45

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

3,4,5-Trifluorobenzoic acid
Oxalyl chloride

DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

[18F]/19F exchange in fluorine containing compounds for potential use in 18F-labelling strategies. Blom E, et al.

J. Labelled Comp. Radiopharm. 52(12) , 504-511, (2009)

2-NITRO-3,4,5-TRIFLUOROBENZOYL CHLORIDE
3 4 5-TRIFLUOROBENZOYL CHLORIDE
3-bromo-2,4,5-trifluorobenzoyl chloride
3-Chloro-2,4,5-trifluorobenzoyl chloride
2,3,5-Trifluorobenzoyl chloride
2,3,4-Trifluorobenzoyl chloride
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
7-phenyl-2-(trifluoromethyl)pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-6(7H)-one
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide