Benzamide,2-hydroxy-N,N-dimethyl-

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Names

[ CAS No. ]:
1778-08-1

[ Name ]:
Benzamide,2-hydroxy-N,N-dimethyl-

[Synonym ]:
2-hydroxy-N,N-dimethyl-benzamide
Salicyldimethylamide
N,N-dimethyl-2-hydroxybenzamide
2-Hydroxy-N,N-diemethylbenzamide
N,N-Dimethyl-salicylamid
Salicylamide,N,N-dimethyl
N,N-dimethyl-salicylamide
Benzamide,2-hydroxy-N,N-dimethyl
salicylic acid dimethylamide

Chemical & Physical Properties

[ Density]:
1.153g/cm3

[ Boiling Point ]:
314.9ºC at 760mmHg

[ Molecular Formula ]:
C9H11NO2

[ Molecular Weight ]:
165.18900

[ Flash Point ]:
144.3ºC

[ Exact Mass ]:
165.07900

[ PSA ]:
40.54000

[ LogP ]:
1.09400

[ Vapour Pressure ]:
0.000244mmHg at 25°C

[ Index of Refraction ]:
1.563

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VN7380000
CHEMICAL NAME :
Salicylamide, N,N-dimethyl-
CAS REGISTRY NUMBER :
1778-08-1
BEILSTEIN REFERENCE NO. :
2361721
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C9-H11-N-O2
MOLECULAR WEIGHT :
165.21
WISWESSER LINE NOTATION :
QR BVN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 108,450,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 108,450,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 86,120,1966

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1N1&VR
  • Phenyl N,N-dimethylcarbamate
  • Dimethylamine
  • Salicylic acid
  • Acetylsalicyloyl chloride
  • Phenyl salicylate
  • N,N-dimethyl-7-oxabicyclo[4.1.0]hepta-2,4-diene-6-carboxamide
  • N,N-Dimethylformamide
  • 2-(Phenoxycarbonyl)phenolate
  • Methyl salicylate

DownStream

  • 2-DIMETHYLAMINOMETHYLPHENOL (CONTAINS PHENOL)
  • Benzamide,2-hydroxy-N-methyl-

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • Benzamide,2-hydroxy-N,N-dimethyl-3-nitro
  • 2-(Dimethylamino)ethanol
  • Benzamide,3-cyclohexyl-2-hydroxy-N,N-dimethyl-
  • Cyclopentanecarboxamide, 2-hydroxy-N,N-dimethyl-, cis- (9CI)
  • Benzenebutanamide, 2-hydroxy-N,N-dimethyl-gamma-phenyl-
  • Benzenecarbothioamide, 2-hydroxy-N,N-dimethyl-
  • N-(6-fluoro-1,3-dimethyl-2,2-dioxido-1,3-dihydrobenzo[c][1,2,5]thiadiazol-5-yl)-1-(methylsulfonyl)piperidine-4-carboxamide
  • 3-cyano-N-(6-fluoro-1,3-dimethyl-2,2-dioxido-1,3-dihydrobenzo[c][1,2,5]thiadiazol-5-yl)benzamide
  • N-(6-fluoro-1,3-dimethyl-2,2-dioxido-1,3-dihydrobenzo[c][1,2,5]thiadiazol-5-yl)-8-methoxy-2-oxo-2H-chromene-3-carboxamide
  • N-(6-fluoro-1,3-dimethyl-2,2-dioxido-1,3-dihydrobenzo[c][1,2,5]thiadiazol-5-yl)benzo[c][1,2,5]thiadiazole-5-carboxamide
  • 5-chloro-N-(6-fluoro-1,3-dimethyl-2,2-dioxido-1,3-dihydrobenzo[c][1,2,5]thiadiazol-5-yl)thiophene-2-carboxamide
  • 2-(3,5-dimethylisoxazol-4-yl)-N-(6-fluoro-1,3-dimethyl-2,2-dioxido-1,3-dihydrobenzo[c][1,2,5]thiadiazol-5-yl)acetamide
  • 2-(4,5-dimethyl-6-oxopyrimidin-1(6H)-yl)-N-(6-fluoro-1,3-dimethyl-2,2-dioxido-1,3-dihydrobenzo[c][1,2,5]thiadiazol-5-yl)acetamide
  • N-(6-fluoro-1,3-dimethyl-2,2-dioxido-1,3-dihydrobenzo[c][1,2,5]thiadiazol-5-yl)furan-3-carboxamide
  • N-(6-fluoro-1,3-dimethyl-2,2-dioxido-1,3-dihydrobenzo[c][1,2,5]thiadiazol-5-yl)-1-methyl-3-(thiophen-2-yl)-1H-pyrazole-5-carboxamide
  • Tert-butyl 2-((6-fluoro-1,3-dimethyl-2,2-dioxido-1,3-dihydrobenzo[c][1,2,5]thiadiazol-5-yl)carbamoyl)pyrrolidine-1-carboxylate