2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid

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Names

[ CAS No. ]:
178306-51-9

[ Name ]:
2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid

[Synonym ]:
3-methoxy-2-hydroxy-3,3-diphenylpropionic acid
FD7217
hydroxymethoxydiphenylpropanoicacid
Benzenepropanoic acid, α-hydroxy-β-methoxy-β-phenyl-
2-hydroxy-3-methoxy-3,3-diphenyl propionic acid
2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid
2-hydroxy-3-methoxy-3,3-diphenyl propanoic acid
rac-2-hydroxy-3-methoxy-3,3-diphenylpropionic acid

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
430.3±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H16O4

[ Molecular Weight ]:
272.296

[ Flash Point ]:
158.4±22.2 °C

[ Exact Mass ]:
272.104858

[ PSA ]:
66.76000

[ LogP ]:
4.10

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.592

Safety Information

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate
  • Benzophenone
  • 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid
  • Methyl 3,3-diphenyl-2-oxiranecarboxylate

DownStream

  • (R)-Ambrisentan
  • Darusentan
  • 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid
  • Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate
  • (S)-Methyl 2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoate

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid
  • (2R)-2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid
  • 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid methyl ester
  • (S)-2-hydroxy-3-methoxy-3,3-diphenylpropanoic acid methyl ester
  • DARUSENTAN
  • rac Ambrisentan
  • 2-Fluoro-4-methoxy-5-(prop-2-en-1-yl)benzonitrile
  • 3-(2,3-Dihydroxypropyl)benzonitrile
  • 4-Sulfamoyl-7-aminobenzofurazan
  • 2-ethenyl-4-(1,3-oxazol-2-yl)-3H-isoindol-1-one
  • Methyl 3-ethenyl-4-methylthiophene-2-carboxylate
  • 4-(Chloromethyl)-2,4-dimethylheptane
  • 5-allyl-4-bromo-2-benzofuran-1(3H)-one
  • Tert-butyl ethyl methyl(2-methyl-6-nitropyridin-3-yl)propanedioate
  • 5-Bromo-3-(hydroxymethyl)thiophene-2-carboxylic acid
  • 5-[(Tert-butyldimethylsilyl)oxy]-2-methylaniline
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