Src Inhibitor-1

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Names

[ CAS No. ]:
179248-59-0

[ Name ]:
Src Inhibitor-1

[Synonym ]:
6,7-Dimethoxy-N-(4-phenoxyphenyl)quinazolin-4-amine
Src Kinase Inhikitor
Src Kinase Inhibitor I
6,7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine
Src-l1
4-Quinazolinamine, 6,7-dimethoxy-N-(4-phenoxyphenyl)-
Src Inhibitor-1
KIN001-030
Src Inhibitor 1

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
528.2±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C22H19N3O3

[ Molecular Weight ]:
373.405

[ Flash Point ]:
273.2±30.1 °C

[ Exact Mass ]:
373.142639

[ PSA ]:
65.50000

[ LogP ]:
4.90

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.665

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335-H413

[ Precautionary Statements ]:
P280-P301 + P312 + P330-P305 + P351 + P338-P337 + P313

[ RIDADR ]:
UN 3077 9 / PGIII

Articles

PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus.

Nat. Commun. 6 , 8100, (2015)

Cholesterol biosynthesis is regulated by transcription factors SREBPs and their escort protein Scap. On sterol depletion, Scap/SREBP complex is transported from endoplasmic reticulum (ER) to the Golgi...

Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity.

J. Hepatol. 62 , 1367-74, (2015)

Sustained c-Jun N-terminal kinase (JNK) activation by saturated fatty acids plays a role in lipotoxicity and the pathogenesis of non-alcoholic steatohepatitis (NASH). We have reported that the interac...

Dasatinib enhances migration of monocyte-derived dendritic cells by reducing phosphorylation of inhibitory immune receptors Siglec-9 and Siglec-3.

Exp. Hematol. 42(9) , 773-82.e1-3, (2014)

The SRC family of kinases (SFKs) is crucial to malignant growth, but also important for signaling in immune cells such as dendritic cells (DCs). These specialized antigen-presenting cells are essentia...


More Articles


Related Compounds

  • Src Inhibitor 3
  • Cyclophilin inhibitor 1
  • Thrombin inhibitor 1
  • mTOR inhibitor-1
  • PTP inhibitor 1
  • Ketohexokinase inhibitor 1
  • tert-butyl N-[4-(3-oxocyclopentyl)phenyl]carbamate
  • rac-(2R,5R)-1-[(prop-2-en-1-yloxy)carbonyl]-5-(trifluoromethyl)piperidine-2-carboxylic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 3-(1-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethyl]-1,3-thiazol-4-yl}-N-methylformamido)-2-methylpropanoic acid
  • 3-(2-Bromo-5-methylphenyl)-3-hydroxy-N-methoxy-N-methylpropanamide
  • [1-(2,1-Benzothiazol-3-yl)azetidin-2-yl]methanamine
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • Methyl 3-(3-fluoro-2-methylphenyl)-3-hydroxypropanoate
  • 3-{[2-(dimethylamino)-4-methylpentyl]carbamoyl}-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
  • 2-(3-Methoxy-2-methylphenyl)ethane-1-thiol