22-alpha-Hydroxy Cholesterol

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Names

[ CAS No. ]:
17954-98-2

[ Name ]:
22-alpha-Hydroxy Cholesterol

[Synonym ]:
Narthesterol
22BF-HYDROXYCHOLESTEROL
22(S)-hydroxycholesterol
(3β,22S)-Cholest-5-ene-3,22-diol
22BETA-HYDROXYCHOLESTEROL
Cholest-5-ene-3,22-diol, (3β,22S)-
22R-OHC
22(R)-HYDROXYCHOLESTEROL

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
513.1±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C27H46O2

[ Molecular Weight ]:
402.65

[ Flash Point ]:
213.5±17.2 °C

[ Exact Mass ]:
402.349792

[ PSA ]:
40.46000

[ LogP ]:
7.66

[ Vapour Pressure ]:
0.0±3.0 mmHg at 25°C

[ Index of Refraction ]:
1.536

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Precursor & DownStream

Precursor

DownStream

  • Cholest-5-en-22-one,3-hydroxy-, (3b)-
  • (5a)-Cholestane

Articles

Oxysterols synergize with statins by inhibiting SREBP-2 in ovarian cancer cells.

Gynecol. Oncol. 135(2) , 333-41, (2014)

Determine mechanisms responsible for enhanced statin efficacy in a novel statin combination we name STOX (STatin-OXysterol).Ovarian cancer cell lines were treated with combinations of statins and oxys...

HBCDD-induced sustained reduction in mitochondrial membrane potential, ATP and steroidogenesis in peripubertal rat Leydig cells.

Toxicol. Appl. Pharmacol. 282(1) , 20-9, (2015)

Hexabromocyclododecane (HBCDD), a brominated flame retardant added to various consumer products, is a ubiquitous environmental contaminant. We have previously shown that 6-hour exposure to HBCDD distu...

Tumor necrosis factor alpha may act as an intraovarian mediator of luteinizing hormone-induced oocyte maturation in trout.

Biol. Reprod. 86(1) , 1-12, (2012)

In fish, like in other vertebrates, luteinizing hormone (Lh) is an essential hormone for the completion of oocyte maturation. In salmonid fish (i.e., salmon and trout), oocyte maturation is induced by...


More Articles


Related Compounds

  • 22-hydroxycholesterol
  • 22-Dehydro 25-Hydroxy Cholesterol 3-Acetate
  • 22-hydroxy Docosanoic Acid methyl ester
  • 22-Hydroxy-A'-neogammaceran-23-oic acid
  • 22-hydroxy-25-fluorocholesterol
  • 22-Hydroxy Mifepristone
  • 1-(3-Bromo-phenyl)-1-m-tolyl-ethanol
  • 5-(Piperazin-1-yl)pyridin-2-amine hydrochloride
  • 1-(3-Methoxyphenyl)propan-1-amine hydrochloride
  • Tert-butyl (2-((3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)(methyl)amino)-2-oxoethyl)carbamate
  • 3-(Dimethylamino)-1-[3-(2-methoxy)ethoxyphenyl]-2-propen-1-one
  • 3-(Oxolan-3-yloxy)benzaldehyde
  • Benzamide, 4-bromo-N-[1-ethyl-1-[(hydroxyamino)iminomethyl]propyl]-2-methyl-
  • 4-Cyclopropyl-2-fluorobenzonitrile
  • 6-Isobutoxy-1H-indazol-3-amine
  • Des-(2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetaldehyde) 3-(Chloromethyl) Cefdinir Hydrochloride Salt (>80%)
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