5-Bromo-2-fluorobenzonitrile

Suppliers

Names

[ Name ]:
5-Bromo-2-fluorobenzonitrile

[Synonym ]:
2-Fluoro-5-bromobenzonitrile
3-bromo-6-fluorobenzonitrile
MFCD00143424
3-cyano-4-fluoro-bromobenzene
5-Bromo-2-fluorobenzonitrile
3-bromo-6-fluorobenzenecarbonitrile
5-bromo-2-fluoro-benzonitrile
Benzonitrile, 5-bromo-2-fluoro-
NCR BF EE
Benzonitrile,5-broMo-2-fluoro
3-cyano-4-flurobromobenzene

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
220.4±20.0 °C at 760 mmHg

[ Melting Point ]:
76-81 °C

[ Molecular Formula ]:
C₇H₃BrFN

[ Molecular Weight ]:
200.008

[ Flash Point ]:
87.1±21.8 °C

[ Exact Mass ]:
198.943283

[ PSA ]:
23.79000

[ LogP ]:
1.92

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.578

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S36/37/39-S26-S22-S36

[ RIDADR ]:
3439

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2926909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

5-Bromobenzo[d]isoxazol-3-ylamine
4-Bromo-2-cyanobenzeneacetonitrile
5-Bromo-2-fluorobenzamide
5-(5-BROMO-2-FLUOROPHENYL)-2H-TETRAZOLE
3-Cyano-4-fluorobenzeneboronic acid
2-Fluoro-5-formylbenzonitrile
5-Acetyl-2-fluorobenzonitrile
3-Cyano-4-Fluorophenylboronic Acid, Pinacol Ester
tert-Butyl 4-(4-bromo-2-cyanophenyl)piperazine-1-carboxylate
5-Bromo-1H-indazol-3-amine

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors.

Bioorg. Med. Chem. 14(20) , 6832-46, (2006)

A series of heteroaryl-pyridine containing inhibitors of Akt are reported. The synthesis and structure-activity relationships are discussed, leading to the discovery of a indazole-pyridine analogue (K...

Synthesis of structurally identical fluorine-18 and iodine isotope labeling compounds for comparative imaging.

Bioconjug. Chem. 14(2) , 287-94, (2003)

The synthesis of a benzophenone-based labeling compound designed for comparative imaging studies with both in vivo positron emission tomograph (PET) and single-photon computed tomography (SPECT) and e...

Microwave-assisted synthesis of 3-aminobenzo [b] thiophene scaffolds for the preparation of kinase inhibitors. Bagley MC, et al.

Org. Biomol. Chem. , (2015)