2-Bromo-4,6-dinitroaniline

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Names

[ Name ]:
2-Bromo-4,6-dinitroaniline

[Synonym ]:
2-bromo-4,6-dinitrobenzenamine
Aniline,2-bromo-4,6-dinitro
EINECS 217-329-2
2,4-Dinitro-6-bromanilin
2,4-dinitro-6-bromo-aniline
2-Bromo-4,6-dinitroaniline
2-bromo-4,6-dinitro-aniline
Bromo DNA
Benzenamine,2-bromo-4,6-dinitro
2-Bromo-4,6-dinitroaminobenzene
6-Bromo-2,4-dinitroaniline
Benzenamine, 2-bromo-4,6-dinitro-
MFCD00007146

Chemical & Physical Properties

[ Density]:
2.0±0.1 g/cm3

[ Boiling Point ]:
400.8±40.0 °C at 760 mmHg

[ Melting Point ]:
148-153 ºC

[ Molecular Formula ]:
C₆H₄BrN₃O₄

[ Molecular Weight ]:
262.018

[ Flash Point ]:
196.2±27.3 °C

[ Exact Mass ]:
260.938507

[ PSA ]:
117.66000

[ LogP ]:
3.09

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.707

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BW9303000

CHEMICAL NAME :: Aniline, 2-bromo-4,6-dinitro-

CAS REGISTRY NUMBER :: 1817-73-8

BEILSTEIN REFERENCE NO. :: 0916722

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C6-H4-Br-N3-O4

MOLECULAR WEIGHT :: 262.04

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4100 mg/kg

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 10 ug/plate

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9(Suppl 9),1,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7087 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 737 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
F:Flammable;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
S37/39-S26-S16

[ RIDADR ]:
1325.0

[ WGK Germany ]:
2

[ RTECS ]:
BW9303000

[ Hazard Class ]:
4.1

[ HS Code ]:
2921420090

Precursor & DownStream

Precursor

2,4-Dinitroaniline
2,4-Dinitrochlorobenzene
1,2-dibromo-3,5-dinitrobenzene
2-Bromo-4,6-dinitroanisole
Phenol,2-bromo-4,6-dinitro-
Iodobenzene
1-Bromo-2-chloro-3,5-dinitrobenzene
2,4-Dinitro-N-methylaniline
2-Bromo-4-nitroaniline
N-(2-bromo-4,6-dinitro-phenyl)-hydroxylamine

DownStream

N-[2-[(2-bromo-4,6-dinitrophenyl)azo]-5-(diethylamino)phenyl]acetamide
N-[2-[(2-bromo-4,6-dinitrophenyl)azo]-5-(diethylamino)-4-methoxyphenyl]acetamide
2,6-Dichloro-4-nitroaniline
1-Bromo-3,5-dinitrobenzene
N-[2-[(2-bromo-4,6-dinitrophenyl)azo]-5-(diallylamino)-4-methoxyphenyl]acetamide
2,2'-[[5-acetamido-4-[(2-bromo-4,6-dinitrophenyl)azo]-2-methoxyphenyl]imino]diethyl diacetate
2-Amino-3-bromo-5-nitrobenzonitrile
Phenol,2-bromo-4,6-dinitro-
Ammonia
4-bromo-6-nitro-2-(trifluoromethyl)-1H-benzimidazole

Customs

[ HS Code ]: 2921420090

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Enzyme-linked immunosorbent assays for the sensitive analysis of 2,4-dinitroaniline and 2,6-dinitroaniline in water and soil.

Anal. Bioanal. Chem 391(5) , 1821-35, (2008)

The development and characterization of one rat monoclonal antibody (mAb) for 2,4-dinitroaniline and of two rat mAbs for 2,6-dinitroaniline are described. With the immunization of rats with 2,4,6-trin...

Inter-laboratory evaluation of the bioluminescent Salmonella reverse mutation assay using 10 model chemicals.

Mutagenesis 24(5) , 433-8, (2009)

We have developed the bioluminescent Salmonella reverse mutation assay as a tool for detecting mutagenicity applicable for high-throughput screening of new chemicals. In this study, we report the inte...

Disposition and metabolism of 2-bromo-4,6-dinitroaniline in the male F344 rat.

J. Toxicol. Environ. Health A 17(1) , 37-50, (1986)

The disposition of [14C]-2-bromo-4,6-dinitroaniline (BDNA) was studied in male F344 rats following oral or intravenous (iv) administration. The gastrointestinal absorption of BDNA was nearly complete ...