N-Desmethyl Vinblastine

Names

[ CAS No. ]:
18172-50-4

[ Name ]:
N-Desmethyl Vinblastine

[Synonym ]:
N-Deformylvincristine
N-Desmethylvinblastine
1-Demethyl-vincaleukoblastine
N-Deformylleurocristine

Chemical & Physical Properties

[ Density]:
1.38g/cm3

[ Melting Point ]:
186-188ºC

[ Molecular Formula ]:
C45H56N4O9

[ Molecular Weight ]:
796.94800

[ Exact Mass ]:
796.40500

[ PSA ]:
162.89000

[ LogP ]:
3.98040

[ Index of Refraction ]:
1.673

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YY8180500
CHEMICAL NAME :
Vincaleukoblastine, 1-demethyl-
CAS REGISTRY NUMBER :
18172-50-4
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C45-H56-N4-O9

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
85 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 26,1213,1977

Related Compounds

  • N-Desmethyl Prochlorperazine Dimaleate
  • N-Desmethyl-cis-tramadol HCl
  • N-Desmethyl imatinib mesylate
  • N-DesMethyl N-Ethyl Olanzapine
  • N-Desmethyl Droloxifene-d5
  • N-Desmethyl Trifluoperazine Dihydrochloride
  • 3-((4-Ethoxyphenyl)diazenyl)-4-hydroxy-2,7-naphthalenedisulfonic acid
  • Carbamic acid, [3-[[[(isododecyloxy)carbonyl]amino]methyl]-3,5,5-trimethylcyclohexyl]-, isododecyl ester
  • Cholestan-3-Ol, isooctadecanoate, (3beta,5alpha)-
  • 7-Methoxy-2-methylcinnolinium
  • Astaxanthin dimethylsuccinate
  • 1,4-Benzodioxin-6-ylhydrazine
  • Trisodium 4-amino-3-{[4-(ethenesulfonyl)phenyl]diazenyl}-6-{[4-(ethenesulfonyl)-2-sulfonatophenyl]diazenyl}-5-hydroxynaphthalene-2,7-disulfonate
  • 2,5',5'-trimethyloctahydro-1'H-spiro[1,3-dioxane-5,2'-naphthalene]
  • Sodium (2R)-2-(4-(4-cyano-2-fluorophenoxy)phenoxy)propanoate
  • 3-({4-[(2,3-Dihydroxypropyl)(dimethyl)azaniumyl]-1-hydroxy-2-butanyl}[(perfluoropropyl)sulfonyl]amino)-1-propanesulfonate
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