N-Desmethyl Vinblastine

Names

[ CAS No. ]:
18172-50-4

[ Name ]:
N-Desmethyl Vinblastine

[Synonym ]:
N-Deformylvincristine
N-Desmethylvinblastine
1-Demethyl-vincaleukoblastine
N-Deformylleurocristine

Chemical & Physical Properties

[ Density]:
1.38g/cm3

[ Melting Point ]:
186-188ºC

[ Molecular Formula ]:
C45H56N4O9

[ Molecular Weight ]:
796.94800

[ Exact Mass ]:
796.40500

[ PSA ]:
162.89000

[ LogP ]:
3.98040

[ Index of Refraction ]:
1.673

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YY8180500
CHEMICAL NAME :
Vincaleukoblastine, 1-demethyl-
CAS REGISTRY NUMBER :
18172-50-4
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C45-H56-N4-O9

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
85 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 26,1213,1977

Related Compounds

  • N-Desmethyl Prochlorperazine Dimaleate
  • N-Desmethyl-cis-tramadol HCl
  • N-Desmethyl imatinib mesylate
  • N-DesMethyl N-Ethyl Olanzapine
  • N-Desmethyl Droloxifene-d5
  • N-Desmethyl Trifluoperazine Dihydrochloride
  • 4-(1-Amino-2-hydroxyethyl)-2-bromo-6-methoxyphenol
  • (3S)-3-{[(benzyloxy)carbonyl]amino}-3-(5-chloro-2-fluorophenyl)propanoic acid
  • 3-(1-Amino-2-hydroxyethyl)-2-bromo-6-methoxyphenol
  • (3R)-3-{[(benzyloxy)carbonyl]amino}-3-(4-chloro-2-fluorophenyl)propanoic acid
  • 5-[(1S)-1-amino-2-hydroxyethyl]-4-bromo-2-methoxyphenol
  • (3R)-3-{[(benzyloxy)carbonyl]amino}-3-(5-chloro-2-fluorophenyl)propanoic acid
  • 5-[(1R)-1-Amino-2-hydroxyethyl]-4-bromo-2-methoxyphenol
  • I(2)-D-Glucopyranoside, 4-nitrophenyl, 6-(hydrogen sulfate)
  • 4-[(1S)-1-amino-2-hydroxyethyl]-5-bromo-2-methoxyphenol
  • 1H-2-Benzothiopyran-4-amine, 6-chloro-8-fluoro-3,4-dihydro-, (4S)-
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