Muscimol Hydrobromide

Suppliers

Names

[ Name ]:
Muscimol Hydrobromide

[Synonym ]:
Muscimol hydrobromide
5-(Aminomethyl)-3(2H)-isoxazolone hydrobromide
3(2H)-Isoxazolone,5-(aminomethyl)-,monohydrobromide
3-Hydroxy-5-aminomethylisoxazole hydrobromide
5-Aminomethyl-3-hydroxyisoxazole hydrobromide
5-(Aminomethyl)-3-isoxazolol hydrobromide
5-Aminomethyl-3-isoxaolol-hydrobromid
MFCD00055184
Agarin hydrobromide
5-aminomethyl-isoxazol-3-one,hydrobromide
5-(Aminomethyl)-3-isoxazolol monohydrobromide
5-Aminomethyl-3-isoxyzole hydrobromide

Chemical & Physical Properties

[ Density]:
1.291 g/cm3

[ Boiling Point ]:
325ºC at 760 mmHg

[ Melting Point ]:
172ºC

[ Molecular Formula ]:
C₄H₇BrN₂O₂

[ Molecular Weight ]:
195.01500

[ Flash Point ]:
150.4ºC

[ Exact Mass ]:
193.96900

[ PSA ]:
72.28000

[ LogP ]:
1.49730

[ Vapour Pressure ]:
0.0463mmHg at 25°C

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NY3345000

CHEMICAL NAME :: 3(2H)-Isoxazolone, 5-(aminomethyl)-, monohydrobromide

CAS REGISTRY NUMBER :: 18174-72-6

LAST UPDATED :: 199206

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C4-H6-N2-O2.Br-H

MOLECULAR WEIGHT :: 195.04

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 13844 ug/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Skin and Appendages - hair

REFERENCE :: NEPHBW Neuropharmacology. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.9- 1970- Volume(issue)/page/year: 21,803,1982

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R25

[ Safety Phrases ]:
22-36/37/39-45

[ RIDADR ]:
UN 1544 6

[ RTECS ]:
NY3345000

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Modulation of locomotor activation by the rostromedial tegmental nucleus.

Neuropsychopharmacology 40(3) , 676-87, (2015)

The rostromedial tegmental nucleus (RMTg) is a strong inhibitor of dopamine neurons in the ventral tegmental area (VTA) reported to influence neurobiological and behavioral responses to reward omissio...

Inactivation of the prelimbic or infralimbic cortex impairs decision-making in the rat gambling task.

Psychopharmacology 232 , 4481-91, (2015)

Studies employing the Iowa Gambling Task (IGT) demonstrated that areas of the frontal cortex, including the ventromedial prefrontal cortex, orbitofrontal cortex (OFC), dorsolateral prefrontal cortex, ...

Cholinergic, but not NMDA, receptors in the lateral entorhinal cortex mediate acquisition in trace eyeblink conditioning.

Hippocampus 25 , 1456-64, (2015)

Anatomical and electrophysiological studies collectively suggest that the entorhinal cortex consists of several subregions, each of which is involved in the processing of different types of informatio...