TERT-BUTYL 5-BROMO-1H-INDOLE-1-CARBOXYLATE

Names

[ CAS No. ]:
182344-70-3

[ Name ]:
TERT-BUTYL 5-BROMO-1H-INDOLE-1-CARBOXYLATE

[Synonym ]:
MFCD02090067
Tert-Butyl 5-Bromoindole-1-Carboxylate

Chemical & Physical Properties

[ Density]:
1.37g/cm3

[ Boiling Point ]:
367.9ºC at 760mmHg

[ Melting Point ]:
56-57ºC(lit.)

[ Molecular Formula ]:
C₁₃H₁₄BrNO₂

[ Molecular Weight ]:
296.16000

[ Flash Point ]:
176.3ºC

[ Exact Mass ]:
295.02100

[ PSA ]:
31.23000

[ LogP ]:
4.18700

[ Vapour Pressure ]:
1.33E-05mmHg at 25°C

[ Index of Refraction ]:
1.576

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Structure-activity relationship analysis of the peptide deformylase inhibitor 5-bromo-1H-indole-3-acetohydroxamic acid.

ChemMedChem 4 , 261, (2009)

The lead compound 5-bromoindolyl-3-acetohydroxamic acid (10) was recently identified as a potent inhibitor of bacterial peptide deformylases (PDFs). The synthesis and associated activities of new vari...

Synthesis of heterocyclic allenes via palladium-catalyzed hydride-transfer reaction of propargylic amines.

J. Org. Chem. 70(6) , 2357-60, (2005)

[reaction: see text] Propargylic diisopropylamines containing heterocycles, which were prepared readily from heterocyclic bromides and propargyldiisopropylamine by the Sonogashira coupling reaction, u...

tert-Butyl 5-bromo-3-(cyanomethyl)-1H-indole-1-carboxylate
Tert-butyl 5-bromo-4-formyl-7-methyl-1H-indole-1-carboxylate
tert-Butyl 5-bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate
TERT-BUTYL 5-(BENZYLOXY)-3-BROMO-1H-INDOLE-1-CARBOXYLATE
1-Boc-5-Bromo-3-iodoindole
1-BOC-5-BROMO-3-FORMYLINDOLE
1-(2,3-Dimethoxyphenyl)-3-(4-(3-methoxypiperidin-1-yl)phenyl)urea
5-bromo-N-(2-(4-cyclopropyl-3-(furan-2-yl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)ethyl)nicotinamide
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
methyl (1R,3aS,3bS,5aR,9aR,11aS)-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxylate
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde