azintamide

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Names

[ CAS No. ]:
1830-32-6

[ Name ]:
azintamide

[Synonym ]:
Oragallin
Azinthiamide
Oragal
Oragalin
Oragallin purum
Biloral
Azintamid
Bilipurum
Colerin
Azintamide

Chemical & Physical Properties

[ Density]:
1.27g/cm3

[ Boiling Point ]:
435.3ºC at 760 mmHg

[ Melting Point ]:
97ºC

[ Molecular Formula ]:
C10H14ClN3OS

[ Molecular Weight ]:
259.76

[ Flash Point ]:
217ºC

[ Exact Mass ]:
259.05500

[ PSA ]:
71.39000

[ LogP ]:
2.09050

[ Vapour Pressure ]:
8.88E-08mmHg at 25°C

[ Index of Refraction ]:
1.573

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB5836500
CHEMICAL NAME :
Acetamide, 2-((6-chloro-3-pyridazinyl)thio)-N,N-diethyl-
CAS REGISTRY NUMBER :
1830-32-6
BEILSTEIN REFERENCE NO. :
0885011
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C10-H14-Cl-N3-O-S
MOLECULAR WEIGHT :
259.78
WISWESSER LINE NOTATION :
T6NNJ CG FS1VN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1550 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,266,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
540 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,111,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1150 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,111,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,111,1974

Related Compounds

  • Azintamide
  • 2-(4-Hydroxyoxan-4-yl)bicyclo[2.2.1]heptane-2-carboxylic acid
  • 2-(1-Hydroxy-3,5-dimethylcyclohexyl)-2-methylbutanoic acid
  • (3S)-2-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]({[(9H-fluoren-9-yl)methoxy]carbonyl})amino}propanoyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
  • 3-ethyl-1-(2,2,2-trifluoroethyl)-1H-pyrazole-5-carboxylic acid
  • 3-cyclopropyl-1-(2,2-dimethylpropyl)-1H-pyrazole-5-carboxylic acid
  • 2-(8,8-Dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl)acetic acid
  • 2,2-Difluoro-3-hydroxy-4-methyl-4-phenylpentanoic acid
  • 2,2,3-Trifluoro-3-[4-(propan-2-yl)phenyl]propanoic acid
  • 2,2,3-Trifluoro-3-(2-methyl-1,3-thiazol-4-yl)propanoic acid
  • 3-(3,5-Dimethylphenyl)-2,2,3-trifluoropropanoic acid
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