Erlotinib

Suppliers

Names

[ Name ]:
Erlotinib

[Synonym ]:
Erlotinib base
nchembio866-comp3
4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-
Erlotinib
Tarceva
UNII-J4T82NDH7E
N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine
ERLOTINIB HCL
Erlotinib,OS-774
MFCD07781272
N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
OSI 744

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
553.6±50.0 °C at 760 mmHg

[ Melting Point ]:
223 - 228ºC

[ Molecular Formula ]:
C₂₂H₂₃N₃O₄

[ Molecular Weight ]:
393.436

[ Flash Point ]:
288.6±30.1 °C

[ Exact Mass ]:
393.168854

[ PSA ]:
74.73000

[ LogP ]:
2.39

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.615

[ Storage condition ]:
2~8°C

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

6,7-Bis(2-methoxyethoxy)-4(1H)-quinazolinone
3-Aminophenylacetylene
N'-[2-cyano-4,5-bis(2-methoxyethoxy)phenyl]-N,N-dimethylmethanimidamide
Erlotinib HCl (OSI-744)
4-Chloro-6,7-(2-methoxyethoxy)-quinazoline
1-Iodo-2-methoxyethane
2-AMino-4,5-bis (2-Methoxyethoxy)benzonitrile

DownStream

Related Compounds

Erlotinib
Erlotinib
erlotinib
Erlotinib-d6
Erlotinib HCl
Erlotinib-13C6
3-(Cyclopentyloxy)-5-nitro-1H-indazole
Methyl 6-bromoquinoline-7-carboxylate
2-(Morpholine-4-carbonyl)-4,5,6,7-tetrahydro-1-benzothiophene-5-carboxylic acid
2-(2-Bromo-5-fluorophenyl)-2,2-difluoroethan-1-amine
2-Bromo-5-(pentyloxy)pyridine
(3S)-3-hydroxy-3-(1-methyl-1H-pyrazol-4-yl)propanoic acid
1-(2-Amino-5-methyl-1,3-benzoxazol-7-YL)ethanone
5-(2-Nitrophenyl)-1-(4-phenylphenyl)indole
(R)-(4-Bromo-2,6-difluorophenyl)(cyclopropyl)methanamine
Ethyl 3-(4-chloro-3-ethoxyphenyl)-3-oxopropanoate

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