PD153035 HCl

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Names

[ CAS No. ]:
183322-45-4

[ Name ]:
PD153035 HCl

[Synonym ]:
Tyrphostin AG 1517
N-(3-Bromophenyl)-6,7-dimethoxy-4-quinazolinamine hydrochloride (1:1)
N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride
PD-153035 HYDROCHLORIDE
4-[(3-BROMOPHENYL)AMINO]-6,7-DIMETHOXYQUINAZOLINE HYDROCHLORIDE
4-Quinazolinamine, N-(3-bromophenyl)-6,7-dimethoxy-, hydrochloride (1:1)
N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride (1:1)
PD153035 HCl
PD153035 HCL
SU-5271
AG1517
PD153035 Hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
472.1ºC at 760 mmHg

[ Melting Point ]:
265°C(lit.)

[ Molecular Formula ]:
C16H15BrClN3O2

[ Molecular Weight ]:
396.666

[ Flash Point ]:
239.3ºC

[ Exact Mass ]:
395.003601

[ PSA ]:
56.27000

[ LogP ]:
5.02810

[ Appearance of Characters ]:
white to beige

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
DMSO: soluble2mg/mL, clear (warmed)

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P301 + P310-P305 + P351 + P338

[ Hazard Codes ]:
T

[ Risk Phrases ]:
25-37/38-41

[ Safety Phrases ]:
26-39-45

[ RIDADR ]:
UN 2811 6.1 / PGIII

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

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PLoS Biol. 9 , e1001162, (2011)

In order to metastasize, cancer cells need to acquire a motile phenotype. Previously, development of this phenotype was thought to rely on the acquisition of selected, random mutations and thus would ...

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Mol. Cancer 12 , 167, (2014)

The expression of annexin A6 (AnxA6) in AnxA6-deficient non-invasive tumor cells has been shown to terminate epidermal growth factor receptor (EGFR) activation and downstream signaling. However, as a ...

Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation.

Oncogene 30 , 3234-47, (2011)

Claudin-2 is a unique member of the claudin family of transmembrane proteins, as its expression is restricted to the leaky epithelium in vivo and correlates with epithelial leakiness in vitro. However...


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Related Compounds

  • PD153035
  • EPZ020411 HCl
  • Difelikefalin HCl
  • CPD3.1 HCl
  • Raloxifene HCl
  • TP0427736 HCl
  • 2-(Propane-1-sulfonyl)-2,6-diazaspiro[3.4]octane
  • [5-(4-Ethylphenyl)-1,3-thiazol-4-yl]methanamine
  • Methyl[2-(2-phenyl-1,3-thiazol-5-yl)ethyl]amine
  • 6-Ethylpyrazolo[1,5-a]pyrimidin-3-amine
  • 4-Amino-2-(dimethylamino)-1,3-thiazole-5-carboxylic acid
  • 3-Amino-3-(2-bromo-6-methoxyphenyl)propanoic acid
  • 3-(3-Bromo-5-methoxypyridin-4-yl)butanoic acid
  • 2-Amino-1-(2-bromo-4,5-dimethoxyphenyl)ethan-1-one
  • 4,4-Dimethyl-3-oxo-2-(pyridin-4-yl)pentanenitrile
  • 4-Amino-3-(2-bromo-5-hydroxyphenyl)butanoic acid
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