Rolziracetam

Suppliers

Names

[ CAS No. ]:
18356-28-0

[ Name ]:
Rolziracetam

[Synonym ]:
CI-911
tetrahydro-6H-pyrrolizine-3,5-dione
tetrahydro-pyrrolizine-3,5-dione
Rolziracetam
3,5-Dioxopyrrolizidine

Chemical & Physical Properties

[ Density]:
1.28g/cm3

[ Boiling Point ]:
274.9ºC at 760mmHg

[ Molecular Formula ]:
C7H9NO2

[ Molecular Weight ]:
139.15200

[ Flash Point ]:
130.5ºC

[ Exact Mass ]:
139.06300

[ PSA ]:
37.38000

[ LogP ]:
0.23570

[ Vapour Pressure ]:
0.00526mmHg at 25°C

[ Index of Refraction ]:
1.548

[ Storage condition ]:
2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UY8000000
CHEMICAL NAME :
1H-Pyrrolizine-3,5(2H,6H)-dione, dihydro-
CAS REGISTRY NUMBER :
18356-28-0
BEILSTEIN REFERENCE NO. :
0121236
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H9-N-O2
MOLECULAR WEIGHT :
139.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
7 gm/kg/14D-I
TOXIC EFFECTS :
Liver - other changes Kidney, Ureter, Bladder - other changes Musculoskeletal - other changes
REFERENCE :
TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 17,545,1989

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • methyl β-(5-oxo-2-pyrrolidyl)propionate
  • dimethyl 4-nitroheptanedioate
  • N,2,6-TRIMETHYLANILINE
  • Heptanedinitrile, 4-nitro
  • 4-Oxoheptanedioic acid
  • Methanol
  • Ethanol
  • Ethanoic anhydride
  • 4-aminopimelic acid

DownStream

  • N,2,6-TRIMETHYLANILINE
  • 5-ethyl-2-pentyl-3,4-dihydro-2H-pyrrole
  • 1H-Pyrrolizine,hexahydro-

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%