chlornitrofen
Suppliers
Names
[ CAS No. ]:
1836-77-7
[ Name ]:
chlornitrofen
[Synonym ]:
p-nitrophenyl 2,4,6-trichlorophenyl ether
2,4,6-trichloro-4'-nitro-diphenylether
1,3,5-Trichloro-2-(4-nitrophenoxy)benzene 4-Nitrophenyl 2,4,6-trichlorophenyl ether
MC 338
1,3,5-trichloro-2-(4-nitrophenoxy)benzene
4-nitrophenyl 2,4,6-trichlorophenyl ether
4-nitrophenyl-2,4,6-trichlorophenyl ether
EINECS 217-407-6
Chlornitrofen
CNP 1032
2,4,6-Trichlorophenyl 4-nitrophenyl ether
Chemical & Physical Properties
[ Density]:
1.533 g/cm3
[ Boiling Point ]:
370.4ºC at 760 mmHg
[ Melting Point ]:
105-106°
[ Molecular Formula ]:
C12H6Cl3NO3
[ Molecular Weight ]:
318.54000
[ Flash Point ]:
177.8ºC
[ Exact Mass ]:
316.94100
[ PSA ]:
55.05000
[ LogP ]:
5.87050
[ Index of Refraction ]:
1.731
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KO2700000
- CHEMICAL NAME :
- Ether, p-nitrophenyl 2,4,6-trichlorophenyl
- CAS REGISTRY NUMBER :
- 1836-77-7
- BEILSTEIN REFERENCE NO. :
- 1890443
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C12-H6-Cl3-N-O3
- MOLECULAR WEIGHT :
- 318.54
- WISWESSER LINE NOTATION :
- WNR DOR BG DG FG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >520 mg/m3/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - domestic
- DOSE/DURATION :
- 2680 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 10 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 100 ug/plate
- REFERENCE :
- CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 44,133,1983
Safety Information
[ Symbol ]:
GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H410
[ Precautionary Statements ]:
P273-P501
[ Hazard Codes ]:
Xi: Irritant;F: Flammable;
[ Risk Phrases ]:
50/53
[ Safety Phrases ]:
60-61
[ RIDADR ]:
UN 3077 9 / PGIII
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Mutat. Res. 346(1) , 57-60, (1995)
Three kinds of diphenyl ether herbicides, 4-nitrophenyl 2,4,6-trichlorophenyl ether (CNP, chlornitrofen), 2,4-dichlorophenyl 3-methoxy-4-nitrophenyl ether (chlomethoxynil) and 2,4-dichlorophenyl 3-met...
Food Chem. Toxicol. 37(1) , 69-74, (1999)
We studied the cytotoxic and porphyrinogenic effects of four diphenyl ethers (DPEs), chlornitrofen (CNP), CNP-amino, chlomethoxyfen and bifenox, in rat hepatocytes cultured on Matrigel. Cytotoxicity w...
Bull. Environ. Contam. Toxicol. 39(4) , 555-62, (1987)