leucomycin A6

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Names

[ CAS No. ]:
18361-48-3

[ Name ]:
leucomycin A6

[Synonym ]:
Antibiotic yl-704 B3
Turimycin A3
Platenomycin-B3
Leucomycin V 3-acetate 4b-propanoate
Yl 704 B3
Leucomycin A6
Leukomycin A6

Chemical & Physical Properties

[ Density]:
1.22g/cm3

[ Boiling Point ]:
867ºC at 760mmHg

[ Molecular Formula ]:
C40H65NO15

[ Molecular Weight ]:
799.94200

[ Flash Point ]:
478.1ºC

[ Exact Mass ]:
799.43500

[ PSA ]:
206.05000

[ LogP ]:
2.37730

[ Vapour Pressure ]:
4.52E-35mmHg at 25°C

[ Index of Refraction ]:
1.537

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OH4725500
CHEMICAL NAME :
Leucomycin A6
CAS REGISTRY NUMBER :
18361-48-3
LAST UPDATED :
199512
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C40-H65-N-O15
MOLECULAR WEIGHT :
800.06
WISWESSER LINE NOTATION :
T-16-OV KU MUTJ DOO2 EO1 G1VH I1 JQ P1 FO- BT6OTJ CQ DN1&1 F1 EO- FT6OTJ B1 COV2 DQ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
9600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,810,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 37,1565,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 2,87,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 4,193,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3535309

Related Compounds

  • leucomycin A7
  • Leucomycin V, 4(sup B),9-diacetate 3-propanoate
  • Leucomycin A9
  • Leucomycin A4
  • Leucomycin V 4''-butanoate 3-propanoate
  • Leucomycin A5
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • N1,N4,N4-Trimethyl-2-nitro-1,4-benzenediamine
  • 4-(Methoxymethyl)-1,3-thiazole-5-carboxylic acid
  • 3-[4,6-dimethyl-2-(methylsulfanyl)pyrimidin-5-yl]-N-(4-methanesulfonylphenyl)propanamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde