Leukomycin A8

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Names

[ CAS No. ]:
18361-50-7

[ Name ]:
Leukomycin A8

[Synonym ]:
Turimycin A2
Leukomycin A8
Leucomycin A8

Chemical & Physical Properties

[ Density]:
1.23g/cm3

[ Boiling Point ]:
859.9ºC at 760 mmHg

[ Molecular Formula ]:
C39H63NO15

[ Molecular Weight ]:
785.91500

[ Flash Point ]:
473.9ºC

[ Exact Mass ]:
785.42000

[ PSA ]:
206.05000

[ LogP ]:
1.98720

[ Vapour Pressure ]:
1.85E-34mmHg at 25°C

[ Index of Refraction ]:
1.538

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OH4730000
CHEMICAL NAME :
Leucomycin V, 3,4(sup B)-diacetate
CAS REGISTRY NUMBER :
18361-50-7
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C39-H63-N-O15
MOLECULAR WEIGHT :
786.03
WISWESSER LINE NOTATION :
T-16-OV KU MUTJ DOV1 EO1 G1VH I1 JQ P1 FO- BT6OTJ CQ DN1&1 F1 EO- FT6OTJ B1 COV1 DQ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3535309
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
970 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 2,88,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3535309

Related Compounds

  • Leukomycin A8
  • buddlejoside A8
  • gibberellin A8-catabolite
  • erastin-A8
  • N-[2-(1-{4-[2-(4-chloro-phenoxy)-acetyl]-piperazin-1-yl}-ethyl)-3-(2-ethoxy-phenyl)-4-oxo-3,4-dihydro-quinazolin-7-yl]-acetamide
  • CPD3325-A8
  • 4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl) 3-methyl 1-methyl-1H-pyrazole-3,4-dicarboxylate
  • methyl 1-{2-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)oxy]-2-oxoethyl}-1H-pyrazole-3-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-(pentan-3-yl)-1H-pyrazole-3-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-chloro-5-(pyridin-2-yl)benzoate
  • 1-tert-butyl 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl) (2R)-piperidine-1,2-dicarboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-methoxy-3-(1H-1,2,3,4-tetrazol-1-yl)benzoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-(5-chloro-1H-indol-1-yl)butanoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-ethyl-4-oxo-1,4-dihydrocinnoline-3-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-methyl-2-(1-methyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 5-(phenylformamido)pentanoate
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