Ethacridine lactate
Suppliers
Names
[ CAS No. ]:
1837-57-6
[ Name ]:
Ethacridine lactate
[Synonym ]:
Ethacridine Lactate
RIVANOL
rivinol
2-Hydroxypropanoic acid - 7-ethoxy-3,9-acridinediamine (1:1)
7-ethoxy-acridine-3,9-diyldiamine,DL lactate
rimaon
MFCD00013149
2-ethoxy-6,9-diaminoacridine lactate
UNII:7T7T2I9823
Propanoic acid, 2-hydroxy-, compd. with 7-ethoxy-3,9-acridinediamine (1:1)
flavitrol
EINECS 217-408-1
ETHODIN
TCMDC-123983
ACRYNOL
metifex
2-Hydroxypropanoic acid - 7-ethoxyacridine-3,9-diamine (1:1)
Vucine
ACRINOL
Ethacridine (lactate)
Chemical & Physical Properties
[ Boiling Point ]:
270 °C(lit.)
[ Melting Point ]:
62-67 °C(lit.)
[ Molecular Formula ]:
C18H21N3O4
[ Molecular Weight ]:
343.377
[ Flash Point ]:
143 °C
[ Exact Mass ]:
343.153198
[ PSA ]:
131.69000
[ LogP ]:
3.56530
[ Vapour Pressure ]:
4.72E-11mmHg at 25°C
[ Water Solubility ]:
soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OD4725000
- CAS REGISTRY NUMBER :
- 1837-57-6
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C15-H15-N3-O.C3-H6-O3
- MOLECULAR WEIGHT :
- 343.42
- WISWESSER LINE NOTATION :
- T C666 BNJ EZ IZ LO2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 120 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Vascular - shock
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 48 gm/kg/30D-C
- TOXIC EFFECTS :
- Endocrine - other changes Endocrine - changes in thymus weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 420 mg/kg/21D-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Endocrine - changes in spleen weight
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Microorganism - not otherwise specified
- DOSE/DURATION :
- 250 mg/L
- REFERENCE :
- PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 56,500,1966 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5763 No. of Facilities: 23 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 23 (estimated)
Safety Information
[ Hazard Codes ]:
Xi,Xn
[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin . R22:Harmful if swallowed. R40:Limited evidence of a carcinogenic effect. R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
[ Safety Phrases ]:
S26-S24/25-S37/39
[ WGK Germany ]:
3
[ RTECS ]:
UT6410000
[ HS Code ]:
2933990090
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%