MRS 1220

Suppliers

Names

[ CAS No. ]:
183721-15-5

[ Name ]:
MRS 1220

[Synonym ]:
MRS 1220
9-Chloro-2-(2-furanyl)-5-((phenylacetyl)amino)-[1,2,4]triazolo[1,5-c]quinazoline
Tocris-1217
MFCD01321046

Chemical & Physical Properties

[ Density]:
1.49g/cm3

[ Molecular Formula ]:
C21H14ClN5O2

[ Molecular Weight ]:
403.82

[ Exact Mass ]:
403.08400

[ PSA ]:
85.32000

[ LogP ]:
4.44510

[ Index of Refraction ]:
1.744

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Fragment-Based Discovery of Subtype-Selective Adenosine Receptor Ligands from Homology Models.

J. Med. Chem. 58 , 9578-90, (2015)

Fragment-based lead discovery (FBLD) holds great promise for drug discovery, but applications to G protein-coupled receptors (GPCRs) have been limited by a lack of sensitive screening techniques and s...

Derivatives of the triazoloquinazoline adenosine antagonist (CGS15943) are selective for the human A3 receptor subtype.

J. Med. Chem. 39 , 4142-4148, (1996)

The adenosine antagonist 9-chloro-2-(2-furanyl)[1,2,4]triazolo[1,5-c]quinazolin-5-amine (CGS15943) binds to human A3 receptors with high affinity (Ki = 14 nM), while it lacks affinity at rat A3 recept...

Pharmacological characterization of novel A3 adenosine receptor-selective antagonists.

Neuropharmacology 36 , 1157-1165, (1997)

The effects of putative A3 adenosine receptor antagonists of three diverse chemical classes (the flavonoid MRS 1067, the 6-phenyl-1,4-dihydropyridines MRS 1097 and MRS 1191, and the triazoloquinazolin...


More Articles

Related Compounds

  • MRS 2219
  • MRS 1845
  • MRS 2690
  • MRS 1477
  • MRS 1523
  • MRS 1706
  • (E)-N-(5-benzyl-1,3,4-thiadiazol-2(3H)-ylidene)-Nalpha-(morpholin-4-ylcarbonyl)-L-phenylalaninamide
  • 2-[3-(4-chlorophenyl)-6-oxopyridazin-1(6H)-yl]-N-[(2E)-5-(tetrahydrofuran-2-yl)-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
  • N-[4-(benzyloxy)phenyl]-2-(6-oxo-3-phenylpyridazin-1(6H)-yl)acetamide
  • 5-((4-Methylpiperazin-1-yl)methyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid
  • N-(2,2-dimethylpropyl)-6-methylpyridin-3-amine
  • N-[4-(acetylamino)phenyl]-2-(benzylamino)-1,3-thiazole-4-carboxamide
  • N-(2,4-dimethoxyphenyl)-2-[3-(2-fluorophenyl)-6-oxopyridazin-1(6H)-yl]acetamide
  • N-(3-chloro-4-fluorophenyl)-2-[3-(3-methoxyphenyl)-6-oxopyridazin-1(6H)-yl]acetamide
  • 2-(benzylamino)-N-(1,3-thiazol-2-yl)-1,3-thiazole-4-carboxamide
  • 3-(4-chloro-1H-indol-1-yl)-1-(thiomorpholin-4-yl)propan-1-one
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