MRS 1220

Suppliers

Names

[ CAS No. ]:
183721-15-5

[ Name ]:
MRS 1220

[Synonym ]:
MRS 1220
9-Chloro-2-(2-furanyl)-5-((phenylacetyl)amino)-[1,2,4]triazolo[1,5-c]quinazoline
Tocris-1217
MFCD01321046

Chemical & Physical Properties

[ Density]:
1.49g/cm3

[ Molecular Formula ]:
C21H14ClN5O2

[ Molecular Weight ]:
403.82

[ Exact Mass ]:
403.08400

[ PSA ]:
85.32000

[ LogP ]:
4.44510

[ Index of Refraction ]:
1.744

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Fragment-Based Discovery of Subtype-Selective Adenosine Receptor Ligands from Homology Models.

J. Med. Chem. 58 , 9578-90, (2015)

Fragment-based lead discovery (FBLD) holds great promise for drug discovery, but applications to G protein-coupled receptors (GPCRs) have been limited by a lack of sensitive screening techniques and s...

Derivatives of the triazoloquinazoline adenosine antagonist (CGS15943) are selective for the human A3 receptor subtype.

J. Med. Chem. 39 , 4142-4148, (1996)

The adenosine antagonist 9-chloro-2-(2-furanyl)[1,2,4]triazolo[1,5-c]quinazolin-5-amine (CGS15943) binds to human A3 receptors with high affinity (Ki = 14 nM), while it lacks affinity at rat A3 recept...

Pharmacological characterization of novel A3 adenosine receptor-selective antagonists.

Neuropharmacology 36 , 1157-1165, (1997)

The effects of putative A3 adenosine receptor antagonists of three diverse chemical classes (the flavonoid MRS 1067, the 6-phenyl-1,4-dihydropyridines MRS 1097 and MRS 1191, and the triazoloquinazolin...


More Articles

Related Compounds

  • MRS 2219
  • MRS 1845
  • MRS 2690
  • MRS 1477
  • MRS 1523
  • MRS 1706
  • Methyl 3-(azetidin-3-yl)-3-hydroxypropanoate
  • 2-methyl-N-(4-methylpyridin-2-yl)-6-(4-(propylsulfonyl)piperazin-1-yl)pyrimidin-4-amine
  • 6-(4-((2-fluorophenyl)sulfonyl)piperazin-1-yl)-2-methyl-N-(4-methylpyridin-2-yl)pyrimidin-4-amine
  • N-[2-(2,3-dioxoquinoxalin-1-ium-1-yl)ethyl]-1-propan-2-ylindole-6-carboxamide
  • N-Methyl-4-(4-(2-pivalamidoethyl)piperidin-1-yl)thieno[3,2-d]pyrimidine-6-carboxamide
  • Tanwusine
  • 4-(4-Ethoxyphenyl)-6-(4-fluorophenyl)pyrimidin-2-amine
  • Ethyl 2-methyl-3-oxo-2,3-dihydropyridazine-4-carboxylate
  • N-(2-((2-methyl-6-((4-methylpyridin-2-yl)amino)pyrimidin-4-yl)amino)ethyl)methanesulfonamide
  • Secophalloidin
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