MRS 1220

Suppliers

Names

[ CAS No. ]:
183721-15-5

[ Name ]:
MRS 1220

[Synonym ]:
MRS 1220
9-Chloro-2-(2-furanyl)-5-((phenylacetyl)amino)-[1,2,4]triazolo[1,5-c]quinazoline
Tocris-1217
MFCD01321046

Chemical & Physical Properties

[ Density]:
1.49g/cm3

[ Molecular Formula ]:
C21H14ClN5O2

[ Molecular Weight ]:
403.82

[ Exact Mass ]:
403.08400

[ PSA ]:
85.32000

[ LogP ]:
4.44510

[ Index of Refraction ]:
1.744

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Fragment-Based Discovery of Subtype-Selective Adenosine Receptor Ligands from Homology Models.

J. Med. Chem. 58 , 9578-90, (2015)

Fragment-based lead discovery (FBLD) holds great promise for drug discovery, but applications to G protein-coupled receptors (GPCRs) have been limited by a lack of sensitive screening techniques and s...

Derivatives of the triazoloquinazoline adenosine antagonist (CGS15943) are selective for the human A3 receptor subtype.

J. Med. Chem. 39 , 4142-4148, (1996)

The adenosine antagonist 9-chloro-2-(2-furanyl)[1,2,4]triazolo[1,5-c]quinazolin-5-amine (CGS15943) binds to human A3 receptors with high affinity (Ki = 14 nM), while it lacks affinity at rat A3 recept...

Pharmacological characterization of novel A3 adenosine receptor-selective antagonists.

Neuropharmacology 36 , 1157-1165, (1997)

The effects of putative A3 adenosine receptor antagonists of three diverse chemical classes (the flavonoid MRS 1067, the 6-phenyl-1,4-dihydropyridines MRS 1097 and MRS 1191, and the triazoloquinazolin...


More Articles

Related Compounds

  • MRS 2219
  • MRS 1845
  • MRS 2690
  • MRS 1477
  • MRS 1523
  • MRS 1706
  • 7-Chloro-1,2-dimethyl-1h-pyrrolo[2,3-c]pyridine
  • [(1E)-2-Isocyanoethenyl]benzene
  • Tert-butyl n-[(4-hydroxyoxan-4-yl)methyl]carbamate
  • 1-(1-Hydroxypropan-2-yl)imidazolidin-2-one
  • N-tert-butyl-3-formyl-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide
  • 1-(4-Amino-3-cyanophenyl)propan-1-one
  • 1-methyl-4-nitro-1H-pyrazol-5-ol
  • 3,3,3-Trifluoro-2-(methylamino)propan-1-ol
  • 6-Chloro-3-fluoro-2-hydroxybenzoicacid
  • 4-Amino-3-ethoxy-N-(2-methoxyethyl)benzamide
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