MRS 1220
Suppliers
Names
[ CAS No. ]:
183721-15-5
[ Name ]:
MRS 1220
[Synonym ]:
MRS 1220
9-Chloro-2-(2-furanyl)-5-((phenylacetyl)amino)-[1,2,4]triazolo[1,5-c]quinazoline
Tocris-1217
MFCD01321046
Chemical & Physical Properties
[ Density]:
1.49g/cm3
[ Molecular Formula ]:
C21H14ClN5O2
[ Molecular Weight ]:
403.82
[ Exact Mass ]:
403.08400
[ PSA ]:
85.32000
[ LogP ]:
4.44510
[ Index of Refraction ]:
1.744
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Articles
J. Med. Chem. 58 , 9578-90, (2015)
Fragment-based lead discovery (FBLD) holds great promise for drug discovery, but applications to G protein-coupled receptors (GPCRs) have been limited by a lack of sensitive screening techniques and s...
J. Med. Chem. 39 , 4142-4148, (1996)
The adenosine antagonist 9-chloro-2-(2-furanyl)[1,2,4]triazolo[1,5-c]quinazolin-5-amine (CGS15943) binds to human A3 receptors with high affinity (Ki = 14 nM), while it lacks affinity at rat A3 recept...
Neuropharmacology 36 , 1157-1165, (1997)
The effects of putative A3 adenosine receptor antagonists of three diverse chemical classes (the flavonoid MRS 1067, the 6-phenyl-1,4-dihydropyridines MRS 1097 and MRS 1191, and the triazoloquinazolin...