Chlorhexidine digluconate

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Names

[ CAS No. ]:
18472-51-0

[ Name ]:
Chlorhexidine digluconate

[Synonym ]:
Maskin
Unisept
Chlorhexamed
1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane
Septeal
(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid - N',N'''''-hexane-1,6-diylbis[N-(4-chlorophenyl)(imidodicarbonimidic diamide)] (2:1)
Betasept
N,N''''-1,6-Hexanediylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)] - D-gluconic acid (1:2)
N,N''-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide di-D-gluconate
Peridex
Rotersept
hibitane
Manusan
chlorohexidine digluconate
Chlorhexidin Bigluconate
N',N'''''-hexane-1,6-diylbis[N-(4-chlorophenyl)(imidodicarbonimidic diamide)] - D-gluconic acid (1:2)
MFCD00083599
Chlorhexidine gluconate
disteryl
chlorhexidine gigluconate
D-Gluconic Acid compd. with N,N''-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide (2:1)
Hibident
Plurexid
Hibidil
N,N''''-Hexane-1,6-diylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)] - D-gluconic acid (1:2)
1,1'-Hexamethylenebis(5-[p-chlorophenyl]biguanide)
chlorhexidine bigluconate
EINECS 242-354-0
STERILON
4-CHLORHEXIDINE DIGLUCONATE
Imidodicarbonimidic diamide, N,N''''-1,6-hexanediylbis[N'-(4-chlorophenyl)-, compd. with D-gluconic acid (1:2)
Corsodyl
UNII-MOR84MUD8E
chlorhexidine D-digluconate
chlorhexidine di-D-gluconate
Hibiscrub
Maskin R
Hibisol
1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide] Digluconate
Hexidine
1,1‘-Hexamethylenebis(5-[p-chlorophenyl]biguanide)
pHiso-Med
orahexal
placout
Chlorhexidine digluconate
abacil
Chlorhexidine (digluconate)

Chemical & Physical Properties

[ Density]:
1.06 g/mL at 25 °C(lit.)

[ Boiling Point ]:
699.3ºC at 760 mmHg

[ Melting Point ]:
134ºC

[ Molecular Formula ]:
C34H54Cl2N10O14

[ Molecular Weight ]:
897.757

[ Flash Point ]:
376.7ºC

[ Exact Mass ]:
896.319824

[ PSA ]:
444.48000

[ Vapour Pressure ]:
0mmHg at 25°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DU1950000
CAS REGISTRY NUMBER :
18472-51-0
LAST UPDATED :
199706
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C22-H30-Cl2-N10.2C6-H12-O7
MOLECULAR WEIGHT :
897.88
WISWESSER LINE NOTATION :
GR DMYUM&MYUM&M6MYUM&MYUM&MR DG &QVYQYQYQYQ1Q 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
24200 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1260 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
12900 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA repair
TEST SYSTEM :
Bacteria - Bacillus subtilis
DOSE/DURATION :
1 mg/L
REFERENCE :
ESKGA2 Eisei Kagaku. Hygienic Chemistry. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1953- Volume(issue)/page/year: 32,171,1986 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3093 No. of Facilities: 4592 (estimated) No. of Industries: 5 No. of Occupations: 36 No. of Employees: 643404 (estimated) No. of Female Employees: 561783 (estimated)

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H410

[ Precautionary Statements ]:
P273-P501

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
N

[ Risk Phrases ]:
50/53

[ Safety Phrases ]:
61

[ RIDADR ]:
UN 3082 9 / PGIII

[ WGK Germany ]:
-

[ HS Code ]:
3004909090

Customs

[ HS Code ]: 3004909090

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Related Compounds

  • Chlorhexidine Impurity B
  • Chlorhexidine Dihydrochloride
  • Chlorhexidine-D8 Dihydrochloride
  • Chlorhexidine
  • Chlorhexidine D8 dihydrochloride
  • Chlorhexidine acetate hydrate
  • N-(3-chloro-4-fluorophenyl)-5-methyl-3-oxo-2-phenyl-3,5-dihydro-2H-pyrazolo[4,3-c]pyridine-7-carboxamide
  • N-(2,4-dimethylphenyl)-5-methyl-3-oxo-2-phenyl-3,5-dihydro-2H-pyrazolo[4,3-c]pyridine-7-carboxamide
  • N-(3,4-dimethoxyphenyl)-5-methyl-3-oxo-2-phenyl-2H,3H,5H-pyrazolo[4,3-c]pyridine-7-carboxamide
  • N-(2,4-dimethoxyphenyl)-5-methyl-3-oxo-2-phenyl-2H,3H,5H-pyrazolo[4,3-c]pyridine-7-carboxamide
  • N-(2,5-dimethoxyphenyl)-5-methyl-3-oxo-2-phenyl-3,5-dihydro-2H-pyrazolo[4,3-c]pyridine-7-carboxamide
  • N-(3-fluoro-4-methylphenyl)-5-methyl-3-oxo-2-phenyl-3,5-dihydro-2H-pyrazolo[4,3-c]pyridine-7-carboxamide
  • 5-methyl-3-oxo-2-phenyl-N-(pyridin-3-yl)-3,5-dihydro-2H-pyrazolo[4,3-c]pyridine-7-carboxamide
  • 5-ethyl-7-(4-(2-fluorophenyl)piperazine-1-carbonyl)-2-phenyl-2H-pyrazolo[4,3-c]pyridin-3(5H)-one
  • 5-ethyl-7-(4-(4-fluorophenyl)piperazine-1-carbonyl)-2-phenyl-2H-pyrazolo[4,3-c]pyridin-3(5H)-one
  • methyl 4-(5-ethyl-3-oxo-2-phenyl-3,5-dihydro-2H-pyrazolo[4,3-c]pyridine-7-carboxamido)benzoate
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