5,6-Dihydro-1,2,3,10-tetramethoxybenzo(a)heptalene-7,9-dione

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Names

[ CAS No. ]:
1850-57-3

[ Name ]:
5,6-Dihydro-1,2,3,10-tetramethoxybenzo(a)heptalene-7,9-dione

[Synonym ]:
7-desacetamido-7-oxocolchicine
Deacetylamino-7-oxocolchicine
5,6-Dihydro-1,2,3,10-tetramethoxybenzo(a)heptalene-7,9-dione
Colchicin-7-one,7-deacetamino
7-oxo-7-deamidocolchicine
7-oxodeacetamidocolchicine
7-deacetamido-7-oxocolchicine
1.2.3.10-Tetramethoxy-5.6-dihydro-benzo<a>heptalen-7.9-dion

Chemical & Physical Properties

[ Density]:
1.28g/cm3

[ Boiling Point ]:
613.3ºC at 760 mmHg

[ Molecular Formula ]:
C20H20O6

[ Molecular Weight ]:
356.36900

[ Flash Point ]:
269.8ºC

[ Exact Mass ]:
356.12600

[ PSA ]:
71.06000

[ LogP ]:
2.87710

[ Vapour Pressure ]:
5.61E-15mmHg at 25°C

[ Index of Refraction ]:
1.589

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Formamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
  • Colchicine
  • diazomethane
  • Trimethylcolchicinic acid
  • Trimethylcolchicinic acid methyl ether

DownStream

Related Compounds

  • (2R)-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanamido]-4-methoxy-4-oxobutanoic acid
  • (2R)-2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbutanamido]-4-methoxy-4-oxobutanoic acid
  • 3-[(4-ethoxy-4-oxobutyl)carbamoyl]-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
  • 3,3-Difluoro-1-(2-fluoro-3-methylphenyl)cyclobutane-1-carboxylic acid
  • 1-(2-Ethylphenyl)-3,3-difluorocyclobutane-1-carboxylic acid
  • 2-{[(2S)-3-(benzyl carboxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]methyl}butanoic acid
  • (2S)-3-[(2S)-3-(benzyl carboxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]-2-hydroxypropanoic acid
  • (2R)-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbutanamido]-4-methoxy-4-oxobutanoic acid
  • (2R)-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,2-difluoropropanamido]-4-methoxy-4-oxobutanoic acid
  • (2R)-2-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}-4-methoxy-4-oxobutanoic acid
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