5,6-Dihydro-1,2,3,10-tetramethoxybenzo(a)heptalene-7,9-dione

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Names

[ CAS No. ]:
1850-57-3

[ Name ]:
5,6-Dihydro-1,2,3,10-tetramethoxybenzo(a)heptalene-7,9-dione

[Synonym ]:
7-desacetamido-7-oxocolchicine
Deacetylamino-7-oxocolchicine
5,6-Dihydro-1,2,3,10-tetramethoxybenzo(a)heptalene-7,9-dione
Colchicin-7-one,7-deacetamino
7-oxo-7-deamidocolchicine
7-oxodeacetamidocolchicine
7-deacetamido-7-oxocolchicine
1.2.3.10-Tetramethoxy-5.6-dihydro-benzo<a>heptalen-7.9-dion

Chemical & Physical Properties

[ Density]:
1.28g/cm3

[ Boiling Point ]:
613.3ºC at 760 mmHg

[ Molecular Formula ]:
C20H20O6

[ Molecular Weight ]:
356.36900

[ Flash Point ]:
269.8ºC

[ Exact Mass ]:
356.12600

[ PSA ]:
71.06000

[ LogP ]:
2.87710

[ Vapour Pressure ]:
5.61E-15mmHg at 25°C

[ Index of Refraction ]:
1.589

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Formamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
  • Colchicine
  • diazomethane
  • Trimethylcolchicinic acid
  • Trimethylcolchicinic acid methyl ether

DownStream

Related Compounds

  • N-(6-bromo-2-morpholinopyrimidin-4-yl)quinolin-3-amine
  • N-[(1S)-1-(4-fluorophenyl)ethyl]-6-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]-4-propan-2-ylpyridazin-3-amine
  • 5-((Diethylamino)methyl)thiazol-2-amine
  • 5-Amino-2-[(1-isopropylpiperidin-4-yl)oxy]pyridine
  • 4-Chloro-5-(2,6-di-4-morpholinyl-4-pyrimidinyl)-2-pyridinamine
  • N-[6-(6-amino-4-chloro-3-pyridinyl)-2-(4-morpholinyl)-4-pyrimidinyl]-3-quinolinamine
  • (E)-4-(4-(3-acetylphenoxy)-6-hydroxypyrimidin-5-yl)but-3-en-2-one
  • 2-(1-(4-aminophenyl)-3,5-dimethyl-1H-pyrazol-4-yl)acetic acid
  • 2-(7-Methyl-2,3-dihydro-1,4-benzodioxin-6-yl)acetic acid
  • Methyl 5-amino-2-ethylbenzoate
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