(2S,4S)-6-FLUORO-2,5-DIOXO-2,3-DIHYDROSPIRO[CHROMENE-4,4-IMIDAZOLIDINE]-2-CARBOXAMIDE

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Names

[ CAS No. ]:
185142-15-8

[ Name ]:
(2S,4S)-6-FLUORO-2,5-DIOXO-2,3-DIHYDROSPIRO[CHROMENE-4,4-IMIDAZOLIDINE]-2-CARBOXAMIDE

Chemical & Physical Properties

[ Density]:
1.105

[ Boiling Point ]:
373.8ºC at 760 mmHg

[ Molecular Formula ]:
C14H25NO4

[ Molecular Weight ]:
271.35300

[ Flash Point ]:
179.9ºC

[ Exact Mass ]:
271.17800

[ PSA ]:
66.84000

[ LogP ]:
2.82310

[ Index of Refraction ]:
1.491

Synthetic Route

Precursor & DownStream

Precursor

  • methyl (2S,5R)-(-)-N-(tert-butyloxycarbonyl)-5-(tert-butylpyrrolidine)-2-carboxylate
  • Pivaloyl chloride
  • (S)-6,6-dimethyl-5-oxo-2-((9-phenyl-9H-fluoren-9-yl)amino)heptanoic acid
  • (2S)-4-(methoxycarbonyl)-6,6-dimethyl-5-oxo-2-(tritylamino)heptanoic acid
  • Di-tert-butyl dicarbonate

DownStream