5a-Androstane-3a,17b-diol
Suppliers
Names
[ CAS No. ]:
1852-53-5
[ Name ]:
5a-Androstane-3a,17b-diol
[Synonym ]:
5a-androstane-3a,17b-diol
5A-ANDROSTAN-3A,17SS-DIOL
5alpha-androstane-3alpha,17beta-diol
dihydroandrosterone
DIHYDROANDROSTANEDIOL
[3H]-Hombreol
Hombreol
Etiocholane-3alpha,17beta-diol
EINECS 217-447-4
Androstane-3alpha,17beta-diol
5-ANDROSTANEDIOL
5.α.-Androstane-3.α.,17.β.-androstanediol
5A-ANDROSTAN-3A,17B-DIOL
MFCD00003676
Chemical & Physical Properties
[ Density]:
1.09g/cm3
[ Boiling Point ]:
415ºC at 760 mmHg
[ Molecular Formula ]:
C19H32O2
[ Molecular Weight ]:
292.45600
[ Exact Mass ]:
292.24000
[ PSA ]:
40.46000
[ LogP ]:
3.75090
[ Vapour Pressure ]:
1.27E-08mmHg at 25°C
[ Index of Refraction ]:
1.546
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BV8044310
- CHEMICAL NAME :
- 5-alpha-Androstane-3-alpha,17-beta-diol
- CAS REGISTRY NUMBER :
- 1852-53-5
- BEILSTEIN REFERENCE NO. :
- 2694353
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C19-H32-O2
- MOLECULAR WEIGHT :
- 292.51
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 48 mg/kg
- SEX/DURATION :
- male 6 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
- REFERENCE :
- JSTBBK Journal of Steroid Biochemistry. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 0BW, UK) V.1- 1969- Volume(issue)/page/year: 18,397,1983
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- DOSE :
- 8 mg/kg
- SEX/DURATION :
- female 13-20 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - urogenital system
- REFERENCE :
- ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21203) V.1- 1917- Volume(issue)/page/year: 99,1490,1976
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- DOSE :
- 40 mg/kg
- SEX/DURATION :
- female 13-20 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - skin and skin appendages
- REFERENCE :
- ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21203) V.1- 1917- Volume(issue)/page/year: 99,1490,1976
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- DOSE :
- 200 ug/kg
- SEX/DURATION :
- male 20 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 89,69,1990
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xn
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
BV8044310
Synthetic Route
Precursor & DownStream
Precursor
DownStream
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