Benzoicacid, 3-[bis(2-chloroethyl)amino]-4-methyl-, methyl ester

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Names

[ CAS No. ]:
18583-88-5

[ Name ]:
Benzoicacid, 3-[bis(2-chloroethyl)amino]-4-methyl-, methyl ester

[Synonym ]:
3-(N,N-Bis-<2-chlor-ethyl>-amino)-4-methyl-benzoesaeure-methylester
3-[Bis(2-chloroethyl)amino]-p-toluic acid methyl ester
3-[Bis(2-chloroethyl)amino]-4-methylbenzoic acid methyl ester

Chemical & Physical Properties

[ Density]:
1.222g/cm3

[ Boiling Point ]:
401.9ºC at 760 mmHg

[ Molecular Formula ]:
C13H17Cl2NO2

[ Molecular Weight ]:
290.18600

[ Flash Point ]:
196.9ºC

[ Exact Mass ]:
289.06400

[ PSA ]:
29.54000

[ LogP ]:
3.06560

[ Vapour Pressure ]:
1.14E-06mmHg at 25°C

[ Index of Refraction ]:
1.554

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XU1630000
CHEMICAL NAME :
p-Toluic acid, 3-(bis(2-chloroethyl)amino)-, methyl ester
CAS REGISTRY NUMBER :
18583-88-5
LAST UPDATED :
199707
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C13-H17-Cl2-N-O2
MOLECULAR WEIGHT :
290.21
WISWESSER LINE NOTATION :
G2N2GR B1 EVO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
NEOLA4 Neoplasma. (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4- 1957- Volume(issue)/page/year: 27,271,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 12,161,1969

Safety Information

[ HS Code ]:
2922499990

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%


Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-[4-(Bromomethyl)phenoxy]-1,4-difluorobenzene
  • 5-Bromo-4-butoxypyridin-3-amine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine