2,4-DIAMINO-6-METHYL-5-PHENYLPYRIMIDINE
Suppliers
Names
[ CAS No. ]:
18588-50-6
[ Name ]:
2,4-DIAMINO-6-METHYL-5-PHENYLPYRIMIDINE
[Synonym ]:
2,4-Diamino-6-methyl-5-phenylpyrimidine
2,4-Diamino-5-phenyl-6-methylpyrimidine
Pyrimidine,2,4-diamino-6-methyl-5-phenyl
2,4-Diamino-5-phenyl-6-methylpyrimidin
6-Methyl-5-phenyl-2,4-pyrimidinediamine
6-methyl-5-phenyl-pyrimidine-2,4-diyldiamine
6-methyl-5-phenyl-pyrimidine-2,4-diamine
IEM-687
6-Methyl-5-phenyl-pyrimidin-2,4-diyldiamin
Chemical & Physical Properties
[ Density]:
1.236g/cm3
[ Boiling Point ]:
431.9ºC at 760 mmHg
[ Molecular Formula ]:
C11H12N4
[ Molecular Weight ]:
200.24000
[ Flash Point ]:
244.9ºC
[ Exact Mass ]:
200.10600
[ PSA ]:
77.82000
[ LogP ]:
2.77880
[ Vapour Pressure ]:
1.16E-07mmHg at 25°C
[ Index of Refraction ]:
1.667
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UV8198000
- CHEMICAL NAME :
- Pyrimidine, 2,4-diamino-6-methyl-5-phenyl-
- CAS REGISTRY NUMBER :
- 18588-50-6
- BEILSTEIN REFERENCE NO. :
- 0012007
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C11-H12-N4
- MOLECULAR WEIGHT :
- 200.27
- WISWESSER LINE NOTATION :
- T6N CNJ BZ DZ ER& F1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 50 mg/kg
- SEX/DURATION :
- female 14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - cytological changes (including somatic cell genetic material)
- REFERENCE :
- SJDBA9 Soviet Journal Developmental Biology (English Translation). Translation of Ontogenez. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.1- 1970- Volume(issue)/page/year: 7,45,1976
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 25 mg/kg
- SEX/DURATION :
- female 9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- REFERENCE :
- AAGEAA Arkhiv Anatomii, Gistologii i Embriologii. Archives of Anatomy, Histology and Embryology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-101, 1916-91. Discontinued Volume(issue)/page/year: 71(7),29,1976
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 100 mg/kg
- SEX/DURATION :
- female 9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- REFERENCE :
- AAGEAA Arkhiv Anatomii, Gistologii i Embriologii. Archives of Anatomy, Histology and Embryology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-101, 1916-91. Discontinued Volume(issue)/page/year: 71(7),29,1976
Safety Information
[ HS Code ]:
2933599090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%