2,5-diphenyl-3H-thieno[2,3-d]pyrimidin-4-one

Names

[ CAS No. ]:
18593-68-5

[ Name ]:
2,5-diphenyl-3H-thieno[2,3-d]pyrimidin-4-one

[Synonym ]:
4-Hydroxy-2,5-diphenyl-thieno<2,3-d>pyrimidin

Chemical & Physical Properties

[ Density]:
1.32g/cm3

[ Molecular Formula ]:
C18H12N2OS

[ Molecular Weight ]:
304.36600

[ Exact Mass ]:
304.06700

[ PSA ]:
74.25000

[ LogP ]:
4.73090

[ Index of Refraction ]:
1.714

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ9094200
CHEMICAL NAME :
Thieno(2,3-d)pyrimidin-4(1H)-one, 2,5-diphenyl-
CAS REGISTRY NUMBER :
18593-68-5
LAST UPDATED :
199403
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C18-H12-N2-O-S
MOLECULAR WEIGHT :
304.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 19,420,1984

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • 3,5-diphenyl-2-sulfanylidene-1H-thieno[2,3-d]pyrimidin-4-one
  • 2-mercapto-3,6-diphenyl-3H-thieno[2,3-d]pyrimidin-4-one
  • 3-AMINO-2,5,6-TRIMETHYL-3H-THIENO[2,3-D]PYRIMIDIN-4-ONE
  • 4-hydroxyequilin
  • 2-(4-methoxyphenyl)-3H-thieno[2,3-d]pyrimidin-4-one
  • 2-MERCAPTO-5-PHENYL-3H-THIENO[2,3-D]PYRIMIDIN-4-ONE
  • methyl 6-(3,4-difluorophenyl)-1-(1,1-dioxidotetrahydrothiophen-3-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
  • methyl 1-(1,1-dioxidotetrahydrothiophen-3-yl)-6-(4-methoxyphenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
  • methyl 6-(4-acetamidophenyl)-1-(1,1-dioxidotetrahydrothiophen-3-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
  • Methyl 1-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)-1,5,6,7-tetrahydrocyclopenta[b]pyrazolo[4,3-e]pyridine-4-carboxylate
  • methyl 1-(1,1-dioxidotetrahydrothiophen-3-yl)-6-isopropyl-3-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
  • methyl 1-(1,1-dioxidotetrahydrothiophen-3-yl)-6-(furan-2-yl)-3-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
  • methyl 1-(1,1-dioxidotetrahydrothiophen-3-yl)-6-isopropyl-3-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
  • methyl 6-cyclopropyl-1-(1,1-dioxidotetrahydrothiophen-3-yl)-3-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
  • methyl 3-(4-chlorophenyl)-6-cyclopropyl-1-(1,1-dioxidotetrahydrothiophen-3-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
  • methyl 6-cyclopropyl-1-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
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