4-[bis(2-chloroethyl)amino]-2-methylbenzoic acid

Names

[ CAS No. ]:
18595-03-4

[ Name ]:
4-[bis(2-chloroethyl)amino]-2-methylbenzoic acid

Chemical & Physical Properties

[ Density]:
1.302g/cm3

[ Boiling Point ]:
442.5ºC at 760 mmHg

[ Molecular Formula ]:
C12H15Cl2NO2

[ Molecular Weight ]:
276.15900

[ Flash Point ]:
221.4ºC

[ Exact Mass ]:
275.04800

[ PSA ]:
40.54000

[ LogP ]:
2.97720

[ Vapour Pressure ]:
1.31E-08mmHg at 25°C

[ Index of Refraction ]:
1.587

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XU1589000
CHEMICAL NAME :
o-Toluic acid, 4-(bis(2-chloroethyl)amino)-
CAS REGISTRY NUMBER :
18595-03-4
LAST UPDATED :
199707
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C12-H15-Cl2-N-O2
MOLECULAR WEIGHT :
276.18
WISWESSER LINE NOTATION :
QVR B1 DN2G2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
57600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRMBAZ Farmacia (Bucharest). (Rompresfilatelia, POB 12-201, Bucharest, Romania) V.1- 1953- Volume(issue)/page/year: 17,473,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
58 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
NEOLA4 Neoplasma. (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4- 1957- Volume(issue)/page/year: 27,271,1980

Related Compounds

  • 4-[Bis(2-chloroethyl)amino]-m-toluic acid
  • 4-[bis(2-chloroethyl)amino]-2-hydroxy-benzoic acid
  • [[4-[bis(2-chloroethyl)amino]-2-methyl-phenyl]methylideneamino]thiourea
  • 4-[[bis(2-chloroethyl)amino-(2-chloroethoxy)phosphoryl]amino]butan-1-ol
  • 4-[[bis(2-chloroethyl)amino-(2-chloroethylamino)phosphoryl]amino]butan-2-ol
  • 4-[bis(2-chloroethyl)amino]-2-chloro-benzaldehyde
  • 1-(4-Chloro-butyl)-4-(2,4-dimethyl-thiazol-5-yl)-1H-pyrimidin-2-one
  • 1-(4-chlorobutyl)-5-phenyl-2(1H)-pyrimidinone
  • 4-(2-Methyl-pyridin-4-yl)-1H-pyrimidin-2-one
  • 2-Methanesulfonyl-4-(6-methyl-pyridin-2-yl)-pyrimidine
  • 1-(4-Chloro-butyl)-4-pyridin-3-yl-1H-pyrimidin-2-one
  • Tert-butyl 4-hydroxy-4-(pyrrolidin-1-ylmethyl)piperidine-1-carboxylate
  • 2-Ethyl-6-methylnicotinaldehyde
  • (2S,4S)-4-(4-Acetylphenoxy)-1-(tert-butoxy-carbonyl)-2-pyrrolidinecarboxylic acid
  • 2-[(E)-1-Benzoyl-2-(dimethylamino)ethenyl]-1H-isoindole-1,3(2H)-dione
  • Ethyl 3-[(cyclopentylmethyl)amino][1,2,4]triazolo[4,3-a]pyridine-6-carboxylate
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