Zibotentan (ZD4054)

Suppliers

Names

[ Name ]:
Zibotentan (ZD4054)

[Synonym ]:
N-(3-Methoxy-5-methyl-2-pyrazinyl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]-3-pyridinesulfonamide
Zd 4054
S1456_Selleck
ZD4054
Zibotentan

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
637.0±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₁₆N₆O₄S

[ Molecular Weight ]:
424.433

[ Flash Point ]:
339.0±34.3 °C

[ Exact Mass ]:
424.095367

[ PSA ]:
141.37000

[ LogP ]:
2.38

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.628

[ Storage condition ]:
-20°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Precautionary Statements ]:
P301 + P312 + P330

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
UT7937700

Articles

A phase I study of zibotentan (ZD4054) in patients with metastatic, castrate-resistant prostate cancer. Schelman WR et al

Invest. New Drugs 29(1) , 118-25, (2011)

3-(Dimethyl-1,2-oxazol-4-yl)-5-ethyl-1,2-oxazole-4-carboxylic acid
5-ethyl-3-(1-methyl-1H-1,2,3-triazol-4-yl)-1,2-oxazole-4-carboxylic acid
3-(6-Bromopyridin-3-yl)-5-ethyl-1,2-oxazole-4-carboxylic acid
3-(5-Methylthiophen-2-yl)-5-(propan-2-yl)-1,2-oxazole-4-carboxylic acid
5-(Propan-2-yl)-3-(1,3-thiazol-2-yl)-1,2-oxazole-4-carboxylic acid
3-(1-methyl-1H-imidazol-2-yl)-5-propyl-1,2-oxazole-4-carboxylic acid
N-[4-(trifluoromethyl)pyrrolidin-3-yl]acetamide
2-chloro-N-(piperidin-3-yl)propanamide
1-[3-(Hydroxymethyl)cyclopentyl]-3-(propan-2-yl)urea
Sodium 3,5-dichloro-4-(2-methoxyethoxy)benzene-1-sulfinate

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