5-ethyl-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione

Names

[ Name ]:
5-ethyl-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione

[Synonym ]:
homo-camptothecin
3H,15H-Oxepino(3',4':6,7)indolizino(1,2-b)quinoline-3,15-dione,5-ethyl-1,4,5,13-tetrahydro-5-hydroxy
(+/-)-E-Homocamptothecin
UNII-33SH2P87CX
rac-homocamptothecin
5-ethyl-1,4,5,13-tetrahydro-5-hydroxy-3H,15H-oxepino[3',4': 6,7]indolizino[1,2-b]quinoline-3,15-dione

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₁₈N₂O₄

[ Molecular Weight ]:
362.37900

[ Exact Mass ]:
362.12700

[ PSA ]:
81.42000

[ LogP ]:
2.46970

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

tert-butyl 3-hydroxy-3-(3-hydroxymethyl-4-oxo-4,6-dihydroindolixino[1,2-b]quinolin-2-yl)pentanoate
1-Phenylethanamine
Campathecin
(-)-O,21-dihydrocamptothecin