4-Hydroxyphenoxyacetic Acid

Suppliers

Names

[ Name ]:
4-Hydroxyphenoxyacetic Acid

[Synonym ]:
4-(Carboxymethoxy)phenol
(4-hydroxy-phenoxy)-acetic acid
MFCD00014362
p-hydroxy-phenoxyacetic acid
Hydrochinon-mono-glykolsaeure
4-Hydroxypheoxyacetate
EINECS 217-525-8
(4-Hydroxyphenoxy)acetic acid
(4-Hydroxy-phenoxy)-essigsaeure
Acetic acid,(4-hydroxyphenoxy)
4-Hydroxyphenoxyacetic Acid

Chemical & Physical Properties

[ Density]:
1.367g/cm3

[ Boiling Point ]:
372.6ºC at 760mmHg

[ Melting Point ]:
154-157 °C(lit.)

[ Molecular Formula ]:
C₈H₈O₄

[ Molecular Weight ]:
168.14700

[ Flash Point ]:
158.3ºC

[ Exact Mass ]:
168.04200

[ PSA ]:
66.76000

[ LogP ]:
0.85560

[ Vapour Pressure ]:
3.27E-06mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Methyl 2-(4-hydroxyphenoxy)acetate
Chloroacetic acid
Hydroquinone
(4-Methoxyphenoxy)acetic acid
[4-(Benzyloxy)phenoxy]acetic acid
2,5-Dichloro-1,4-benzoquinone
Arbutin
ethyl 2-(4-hydroxyphenoxy)acetate
Potassium Hydroquinone Monosulfate
Phenol

DownStream

2-(4-hydroxyphenoxy)acetamide
Methyl 2-(4-hydroxyphenoxy)acetate
2-(3,5-dibromo-4-hydroxyphenoxy)acetic acid
2,2'-[1,4-Phenylenebis(oxy)]diacetic acid
4-(2-hydroxyethoxy)phenol
ethyl 2-(4-hydroxyphenoxy)acetate
4-(2-aminoethoxy)phenol,hydrochloride
1,4-dioxaspiro[4.5]deca-6,9-diene-3,8-dione

Articles

Highly efficient individual dispersion of single-walled carbon nanotubes using biocompatible dispersant.

Colloids Surf. B Biointerfaces 102 , 95-101, (2013)

Individual dispersion of single-walled carbon nanotubes (SWNTs) in biocompatible media is of particular interest for diverse biomedical and nanomedicine applications. Herein we present, for the first ...

A synthetic heparin-mimicking polyanionic compound binds to the LDL receptor-related protein and inhibits vascular smooth muscle cell proliferation.

J. Cell. Biochem. 81(1) , 114-27, (2001)

A synthetic heparin-mimicking polyaromatic anionic compound RG-13577 (polymer of 4-hydroxyphenoxy acetic acid and formaldehyde ammonium salt, Mr approximately 5800) exhibits specific binding to vascul...

Design, synthesis, and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hydroxyphenylpyruvate dioxygenase.

Bioorg. Med. Chem. Lett. 12(13) , 1709-13, (2002)

An epoxybenzoquinone, 4-hydroxyphenoxypropionic acid, and 2-hydroxy-3-phenyl-3-butenoic acid derivatives have been designed, synthesized, and evaluated for in vitro inhibition activity against 4-hydro...

2-Chloro-4-hydroxyphenoxyacetic acid
3,5-DIBROMO-4-HYDROXYPHENOXYACETIC ACID
2,5-dichloro-4-hydroxyphenoxyacetic acid
2,3-dichloro-4-hydroxyphenoxyacetic acid
2,4-Dichloro-5-hydroxyphenoxyacetic acid
7-chloro-benzo[1,4]dioxin-2-one
(Z)-3-(6-Methylpyridin-2-yl)acrylic acid
(4-((4-fluorophenyl)sulfonyl)piperazin-1-yl)(1-methyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl)methanone
1-(4-fluorobenzyl)-4-(3-fluorophenyl)pyrazine-2,3(1H,4H)-dione
N-benzyl-2-(4-(3-fluorophenyl)-2,3-dioxo-3,4-dihydropyrazin-1(2H)-yl)acetamide
3-(3,4-Dichlorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde
1-(4-fluorophenyl)-4-isobutylpyrazine-2,3(1H,4H)-dione
1-(2,3-Dimethylphenyl)-4-(prop-2-en-1-yl)-1,2,3,4-tetrahydropyrazine-2,3-dione
1-(3-Methylphenyl)-4-(prop-2-en-1-yl)-1,2,3,4-tetrahydropyrazine-2,3-dione
1-allyl-4-(4-bromophenyl)pyrazine-2,3(1H,4H)-dione
1-allyl-4-(3,4-difluorophenyl)pyrazine-2,3(1H,4H)-dione

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