4-Hydroxyphenoxyacetic Acid

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Names

[ CAS No. ]:
1878-84-8

[ Name ]:
4-Hydroxyphenoxyacetic Acid

[Synonym ]:
4-(Carboxymethoxy)phenol
(4-hydroxy-phenoxy)-acetic acid
MFCD00014362
p-hydroxy-phenoxyacetic acid
Hydrochinon-mono-glykolsaeure
4-Hydroxypheoxyacetate
EINECS 217-525-8
(4-Hydroxyphenoxy)acetic acid
(4-Hydroxy-phenoxy)-essigsaeure
Acetic acid,(4-hydroxyphenoxy)
4-Hydroxyphenoxyacetic Acid

Chemical & Physical Properties

[ Density]:
1.367g/cm3

[ Boiling Point ]:
372.6ºC at 760mmHg

[ Melting Point ]:
154-157 °C(lit.)

[ Molecular Formula ]:
C8H8O4

[ Molecular Weight ]:
168.14700

[ Flash Point ]:
158.3ºC

[ Exact Mass ]:
168.04200

[ PSA ]:
66.76000

[ LogP ]:
0.85560

[ Vapour Pressure ]:
3.27E-06mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methyl 2-(4-hydroxyphenoxy)acetate
  • Chloroacetic acid
  • Hydroquinone
  • (4-Methoxyphenoxy)acetic acid
  • [4-(Benzyloxy)phenoxy]acetic acid
  • 2,5-Dichloro-1,4-benzoquinone
  • Arbutin
  • ethyl 2-(4-hydroxyphenoxy)acetate
  • Potassium Hydroquinone Monosulfate
  • Phenol

DownStream

  • 2-(4-hydroxyphenoxy)acetamide
  • Methyl 2-(4-hydroxyphenoxy)acetate
  • 2-(3,5-dibromo-4-hydroxyphenoxy)acetic acid
  • 2,2'-[1,4-Phenylenebis(oxy)]diacetic acid
  • 4-(2-hydroxyethoxy)phenol
  • ethyl 2-(4-hydroxyphenoxy)acetate
  • 4-(2-aminoethoxy)phenol,hydrochloride
  • 1,4-dioxaspiro[4.5]deca-6,9-diene-3,8-dione

Articles

Highly efficient individual dispersion of single-walled carbon nanotubes using biocompatible dispersant.

Colloids Surf. B Biointerfaces 102 , 95-101, (2013)

Individual dispersion of single-walled carbon nanotubes (SWNTs) in biocompatible media is of particular interest for diverse biomedical and nanomedicine applications. Herein we present, for the first ...

A synthetic heparin-mimicking polyanionic compound binds to the LDL receptor-related protein and inhibits vascular smooth muscle cell proliferation.

J. Cell. Biochem. 81(1) , 114-27, (2001)

A synthetic heparin-mimicking polyaromatic anionic compound RG-13577 (polymer of 4-hydroxyphenoxy acetic acid and formaldehyde ammonium salt, Mr approximately 5800) exhibits specific binding to vascul...

Design, synthesis, and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hydroxyphenylpyruvate dioxygenase.

Bioorg. Med. Chem. Lett. 12(13) , 1709-13, (2002)

An epoxybenzoquinone, 4-hydroxyphenoxypropionic acid, and 2-hydroxy-3-phenyl-3-butenoic acid derivatives have been designed, synthesized, and evaluated for in vitro inhibition activity against 4-hydro...


More Articles

Related Compounds

  • 2-Chloro-4-hydroxyphenoxyacetic acid
  • 3,5-DIBROMO-4-HYDROXYPHENOXYACETIC ACID
  • 2,5-dichloro-4-hydroxyphenoxyacetic acid
  • 2,3-dichloro-4-hydroxyphenoxyacetic acid
  • 2,4-Dichloro-5-hydroxyphenoxyacetic acid
  • 7-chloro-benzo[1,4]dioxin-2-one
  • 3-[(4-chlorophenyl)methyl]-N-(4-methylcyclohexyl)-4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazoline-7-carboxamide
  • 3-(2-Fluoro-5-methylpyridin-4-YL)propan-1-amine
  • N-[6-amino-5-(2,5-dichlorophenyl)pyridin-2-yl]-2,4-dimethoxybenzamide
  • N-(cyclopropylmethyl)-3-(pyridin-2-yloxy)benzamide
  • N-(2-(4-fluorophenoxy)ethyl)-3-(pyridin-2-yloxy)benzamide
  • 2-Bromo-4-cyclopropoxy-N-methylbenzamide
  • 2-[3-(Difluoromethoxy)phenyl]-4-[(3-methylphenyl)methylene]-5(4H)-oxazolone
  • 2-(Chloromethyl)-4-fluoro-3-methylpyridine
  • 3-Cyclopropoxy-6-methoxy-2-(methylthio)pyridine
  • 3-(4-Fluoro-5-methylpyridin-2-YL)propan-1-amine