Phenethylamine, .α.-methyl-m-trifluoromethyl

Names

[ CAS No. ]:
1886-26-6

[ Name ]:
Phenethylamine, .α.-methyl-m-trifluoromethyl

[Synonym ]:
1-(3-trifluoromethylphenyl)-2-amino propane
3(3-trifluoromethylphenyl)-2-aminopropane
[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amine
norfenfluramine
(+/-)-[1-(3-trifluoromethyl)phenyl]-2-propylamine

Chemical & Physical Properties

[ Density]:
1.152g/cm3

[ Boiling Point ]:
215.2ºC at 760mmHg

[ Molecular Formula ]:
C10H12F3N

[ Molecular Weight ]:
203.20400

[ Flash Point ]:
88.9ºC

[ Exact Mass ]:
203.09200

[ PSA ]:
26.02000

[ LogP ]:
3.29540

[ Vapour Pressure ]:
0.15mmHg at 25°C

[ Index of Refraction ]:
1.466

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SI1800000
CHEMICAL NAME :
Phenethylamine, alpha-methyl-m-trifluoromethyl-
CAS REGISTRY NUMBER :
1886-26-6
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H12-F3-N
MOLECULAR WEIGHT :
203.23
WISWESSER LINE NOTATION :
Z1Y1&R CXFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
51 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
17XKAB "International Symposium on Amphetamines and Related Compounds, Proceedings, Mario Negri Institute for Pharmacological Research, Milan, 1969," Costa, E., and S. Garattini, eds., New York, Raven Press, 1970 Volume(issue)/page/year: -,21,1970

Safety Information

[ HS Code ]:
2921499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-(3-(TRIFLUOROMETHYL)PHENYL)-2-NITROPROPENE
  • 3-(Trifluoromethyl)benzaldehyde

DownStream

  • levofenfluramine
  • 3-[[1-Methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]-1-propanol
  • 4-oxo-4-[2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethoxy]butanoic acid
  • 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethanol
  • Benfluorex
  • 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl 4-aminobenzoate
  • 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl 2-chlorobenzoate
  • 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl 2-(4-chlorophenyl)acetate
  • 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl cyclopropanecarboxylate
  • 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl 4-fluorobenzoate

Customs

[ HS Code ]: 2921499090

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Related Compounds

  • Phenethylamine, alpha-ethyl-alpha-methyl-m-trifluoromethyl-
  • 3-[[α-Methyl-m-(trifluoromethyl)phenethyl]carbamoyl]propenoic acid
  • N-[α-Methyl-m-(trifluoromethyl)phenethyl]-3-piperidinopropionamide
  • N-[α-Methyl-m-(trifluoromethyl)phenethyl]benzamide
  • N-[α-Methyl-m-(trifluoromethyl)phenethyl]-2-phenylacetamide
  • N-[α-Methyl-m-(trifluoromethyl)phenethyl]-3-phenylpropenamide
  • 3,3-difluoro-3-{5H,6H,7H,8H-imidazo[1,2-a]pyridin-2-yl}propanoic acid
  • Methyl 2-hydroxy-2-[1-(pentan-3-yl)cyclopropyl]acetate
  • methyl 5-(2-amino-2-methylpropyl)-1-methyl-1H-pyrazole-4-carboxylate
  • 1-[2-(3-Cyclopropylphenyl)ethyl]cyclopropan-1-ol
  • tert-butyl N-[2-(3-fluoro-4-methylphenyl)-1-oxopropan-2-yl]carbamate
  • 2-[1-(1-{[(Tert-butoxy)carbonyl]amino}cyclopentyl)cyclopropyl]acetic acid
  • Methyl 2-amino-2-(2-fluoro-6-methoxy-4-methylphenyl)acetate
  • 1-(6-Bromo-3-chloro-2-fluorophenyl)cyclopropane-1-carbaldehyde
  • tert-butyl N-[2-(2-bromoethyl)-4-fluorophenyl]carbamate
  • 2-Bromo-6-(1-bromopropan-2-yl)pyridine
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