Epiboxidine hydrochloride

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Names

[ CAS No. ]:
188895-96-7

[ Name ]:
Epiboxidine hydrochloride

[Synonym ]:
7-Azabicyclo(2.2.1)heptane,2-(3-methyl-5-isoxazolyl)-,exo
(+-)-Epiboxidine
exo-2-(3-Methyl-5-isoxazolyl)-7-azabicyclo(2.2.1)heptane

Chemical & Physical Properties

[ Density]:
1.13g/cm3

[ Boiling Point ]:
313.1ºC at 760mmHg

[ Molecular Formula ]:
C10H14N2O

[ Molecular Weight ]:
178.23

[ Flash Point ]:
143.2ºC

[ Exact Mass ]:
214.08700

[ PSA ]:
38.06000

[ LogP ]:
2.72170

[ Vapour Pressure ]:
0.000507mmHg at 25°C

[ Index of Refraction ]:
1.53

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
CL5446415

Articles

Synthesis and nicotinic activity of epiboxidine: an isoxazole analogue of epibatidine.

Eur. J. Pharmacol. 321 , 189-194, (1997)

Synthetic (+/-)-epiboxidine (exo-2-(3-methyl-5-isoxazolyl)-7-azabicyclo[2.2.1]heptane) is a methylisoxazole analog of the alkaloid epibatidine, itself a potent nicotinic receptor agonist with antinoci...

Dithiothreitol causes HIV-1 integrase dimer dissociation while agents interacting with the integrase dimer interface promote dimer formation.

Biochemistry 50 , 1567-81, (2011)

We have developed a homogeneous time-resolved fluorescence resonance energy transfer (FRET)-based assay that detects the formation of HIV-1 integrase (IN) dimers. The assay utilizes IN monomers that e...


More Articles

Related Compounds

  • Tyrocidine, hydrochloride
  • Triprolidine hydrochloride
  • Minoxidil hydrochloride
  • Elacridar hydrochloride
  • dodecylamine hydrochloride
  • Azetidine, hydrochloride, homopolymer (9CI)
  • 3-(4-nitro-1H-pyrazol-3-yl)propanoic acid
  • {2'-chloro-7',8'-dihydro-5'H-spiro[cyclopropane-1,6'-quinoline]-4'-yl}methanol
  • [(1r,3r)-1-(5-Bromo-2-methylphenyl)-3-fluorocyclobutyl]methanol
  • 3-{2-Methoxy-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl}propan-1-ol
  • 2-(3-ethyl-1,2,4-oxadiazol-5-yl)-1-(1-methyl-1H-pyrazol-5-yl)ethan-1-ol
  • 2-{2-Methoxy-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl}ethan-1-ol
  • 2-[3-(1-methoxyethyl)-1,2,4-oxadiazol-5-yl]-1-(1-methyl-1H-pyrazol-5-yl)ethan-1-ol
  • (1S)-2-azido-1-(dimethyl-1,3-thiazol-2-yl)ethan-1-ol
  • 2-azido-1-(1-ethyl-1H-1,2,3-triazol-4-yl)ethan-1-ol
  • (1R)-2-azido-1-(1-cyclobutyl-1H-pyrazol-4-yl)ethan-1-ol
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