(4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1,3-OXAZOLIDIN-2-ONE

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Names

[ CAS No. ]:
189028-95-3

[ Name ]:
(4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1,3-OXAZOLIDIN-2-ONE

[Synonym ]:
3-[5-(p-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-2-oxazolidinone
Ezetimibe Intermediate-6
(S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
3-[(5S)-(4-fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one
(4S)-phenyl-3-[(5S)-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one
(4S)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one
2-Oxazolidinone, 3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-, (4S)-
(4S)-4-phenyl-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one
(S)-3-[5-(4-fluorophenyl)-5(S)-hydroxy-pentanoyl]-4-phenyl-oxazolidin-2-one
(4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1,3-OXAZOLIDIN-2-ONE

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
572.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H20FNO4

[ Molecular Weight ]:
357.375

[ Flash Point ]:
300.2±30.1 °C

[ Exact Mass ]:
357.137634

[ PSA ]:
66.84000

[ LogP ]:
1.71

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.588

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone
  • vinyl acetate
  • (R,S)-3-[5-(4-fluorophenyl)-5-hydroxy-pentanoyl]-4-phenyl-oxazolidin-2-one
  • Isopropanol

DownStream

  • 3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl(aMino)]][4-[triMethylsilyl]-oxy]phenyl]Methyl]-1-oxo-5-[(triMethylsily)-oxy]pentyl]-4-phenyl-(4S)-2-oxazolidinone
  • Ezetimibe

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%