L-Aspartic acid,N-[4-[[(2,4-diamino-5-methyl-6-quinazolinyl)methyl]amino]benzoyl]-
Suppliers
Names
[ CAS No. ]:
18921-70-5
[ Name ]:
L-Aspartic acid,N-[4-[[(2,4-diamino-5-methyl-6-quinazolinyl)methyl]amino]benzoyl]-
[Synonym ]:
Methasquin
N-{4-[(2,4-diamino-5-methyl-quinazolin-6-ylmethyl)-amino]-benzoyl}-aspartic acid
Aspartic acid,N-(p-(((2,4-diamino-5-methyl-6-quinazolinyl)methyl)amino)benzoyl)-,L
N-(p-(((2,4-Diamino-5-methyl-6-quinazolinyl)methyl)amino)benzoyl)-L-aspartic acid
Chemical & Physical Properties
[ Molecular Formula ]:
C21H22N6O5
[ Molecular Weight ]:
438.43700
[ Exact Mass ]:
438.16500
[ PSA ]:
193.55000
[ LogP ]:
2.99870
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CI9320000
- CHEMICAL NAME :
- Aspartic acid, N-(p-(((2,4-diamino-5-methyl-6-quinazolinyl)methyl)am ino)benzoyl)-, L-
- CAS REGISTRY NUMBER :
- 18921-70-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C21-H22-N6-O5
- MOLECULAR WEIGHT :
- 438.49
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50110 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 158 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 17 nmol/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 25,1947,1976