(4S,7R,8S,9S,13Z,16S)-4,8-bis{[tert-butyl(dimethyl)silyl]oxy}-5,5,7,9,13-pentamethyl-16-[(E)-1-methyl-2-(2-methyl-1,3-thiazol-4-yl)ethenyl]oxacyclohexadec-13-ene-2,6-dione

Names

[ CAS No. ]:
189453-35-8

[ Name ]:
(4S,7R,8S,9S,13Z,16S)-4,8-bis{[tert-butyl(dimethyl)silyl]oxy}-5,5,7,9,13-pentamethyl-16-[(E)-1-methyl-2-(2-methyl-1,3-thiazol-4-yl)ethenyl]oxacyclohexadec-13-ene-2,6-dione

Chemical & Physical Properties

[ Molecular Formula ]:
C39H69NO5SSi2

[ Molecular Weight ]:
720.20500

[ Exact Mass ]:
719.44300

[ PSA ]:
102.96000

[ LogP ]:
11.32530

[ Vapour Pressure ]:
0mmHg at 25°C

Synthetic Route

Precursor & DownStream

Precursor

  • (3S,6R,7S,8S,12Z,15S,16E)-3,7-bis{[tert-butyl(dimethyl)silyl]oxy}-15-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-1,3-thiazol-4-yl)-5-oxoheptadeca-12,16-dienoic acid

DownStream

  • epothilone B
  • Epothilone D